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rs12202284
|
|
A |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
|
23548203 |
2013 |
|
rs12203592
|
|
T |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
|
23548203 |
2013 |
|
rs1805007
|
|
C |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
|
23548203 |
2013 |
|
rs8015138
|
|
C |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
|
23548203 |
2013 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results suggested that Arg399Gln variant of <i>XRCC1</i> gene might be a risk factor for NMSC in Asian populations, and Arg194Trp variant of <i>XRCC1</i> gene might be a protective factor for patients with SCC.
|
28761356 |
2017 |
|
rs13181
|
|
|
0.030 |
GeneticVariation |
BEFREE |
On stratified analysis by tumor type, XPD Lys751Gln polymorphism was not associated with increased risk of non-melanoma skin cancer, but was significantly related with increased risk of cutaneous melanoma (Gln/Gln vs Lys/Lys: OR=1.15, 95%CI=1.02-1.29, p=0.023; dominant model: OR=1.09, 95%CI=1.01-1.18, p=0.036).
|
25169498 |
2014 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In the current study, we aim to assess the impact of XRCC1 R399Q and XRCC3 T241M polymorphisms on the risk of NMSC associated with sunlight and arsenic exposure.
|
25218703 |
2014 |
|
rs13181
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our findings indicate a reduced NMSC risk in relation to XPD Asp312Asn and Lys751Gln variants.
|
17687452 |
2007 |
|
rs13181
|
|
|
0.030 |
GeneticVariation |
BEFREE |
To test this hypothesis, a cohort study was conducted to examine the association between XPD Lys751Gln polymorphism and risk of a second primary cancer in individuals with NMSC.
|
15298945 |
2004 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: evidence of gene-environment interaction.
|
11782372 |
2002 |
|
rs1799782
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results suggested that Arg399Gln variant of <i>XRCC1</i> gene might be a risk factor for NMSC in Asian populations, and Arg194Trp variant of <i>XRCC1</i> gene might be a protective factor for patients with SCC.
|
28761356 |
2017 |
|
rs1799793
|
|
|
0.020 |
GeneticVariation |
BEFREE |
However, we did not find any direct association of the rs4134822 and rs1799793 with NMSC risk after covariates adjustment.
|
29113361 |
2017 |
|
rs2228527
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that the G allele of rs2228527 and the G allele of rs2228529 within <i>NER</i> gene, interaction between rs2228529 and current smoking were all associated with increased NMSC risk.
|
29113361 |
2017 |
|
rs2228529
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that the G allele of rs2228527 and the G allele of rs2228529 within <i>NER</i> gene, interaction between rs2228529 and current smoking were all associated with increased NMSC risk.
|
29113361 |
2017 |
|
rs1799782
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our data suggest that the Arg194Trp polymorphism could be associated with nonmelanoma skin cancer and extramammary Paget's disease risk in a Japanese population.
|
22639094 |
2012 |
|
rs2228527
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Using the additive model, two tightly linked functional SNPs in ERCC6 were significantly associated with increased risk of NMSC: rs2228527 (odds ratio (OR) 1.57, 95% confidence interval (CI) 1.20-2.05) and rs2228529 (OR 1.57, 95% CI 1.20-2.05).
|
22336945 |
2012 |
|
rs2228529
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Using the additive model, two tightly linked functional SNPs in ERCC6 were significantly associated with increased risk of NMSC: rs2228527 (odds ratio (OR) 1.57, 95% confidence interval (CI) 1.20-2.05) and rs2228529 (OR 1.57, 95% CI 1.20-2.05).
|
22336945 |
2012 |
|
rs1799793
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our findings indicate a reduced NMSC risk in relation to XPD Asp312Asn and Lys751Gln variants.
|
17687452 |
2007 |
|
rs141193530
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) in GRHL3, rs141193530 (p.P455A), is associated with non-melanoma skin cancer in human patients.
|
29702134 |
2018 |
|
rs25489
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to estimate the association between three coding polymorphisms (Arg399Gln, Arg194Trp, and Arg280His) of the DNA repair gene X-ray repair cross-complementing group 1 (XRCC1) and NMSC susceptibility.
|
28761356 |
2017 |
|
rs2910164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms rs2910164 in miR-146a and rs486907 in the RNASEL gene have both independently been associated with the risk of different cancers, and an interaction between them has been observed in nonmelanoma skin cancer.
|
28654546 |
2017 |
|
rs4134822
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, we did not find any direct association of the rs4134822 and rs1799793 with NMSC risk after covariates adjustment.
|
29113361 |
2017 |
|
rs486907
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms rs2910164 in miR-146a and rs486907 in the RNASEL gene have both independently been associated with the risk of different cancers, and an interaction between them has been observed in nonmelanoma skin cancer.
|
28654546 |
2017 |
|
rs1477800256
|
|
|
0.010 |
GeneticVariation |
BEFREE |
All of the investigated variants showed positive associations with NMSC, with consistent significant results obtained for V60L, D84E, V92M, R151C, R160W, R163Q and D294H: SOR (95%CI) ranged from 1.42 (1.19-1.70) for V60L to 2.66 (1.06-6.65) for D84E variant.
|
26103569 |
2015 |
|
rs1805005
|
|
|
0.010 |
GeneticVariation |
BEFREE |
All of the investigated variants showed positive associations with NMSC, with consistent significant results obtained for V60L, D84E, V92M, R151C, R160W, R163Q and D294H: SOR (95%CI) ranged from 1.42 (1.19-1.70) for V60L to 2.66 (1.06-6.65) for D84E variant.
|
26103569 |
2015 |