Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9315202
rs9315202
0.010 GeneticVariation BEFREE In gene by environment analyses, two KL variants (rs9315202 and rs9563121) interacted with PTSD severity (peak corrected p = 0.044) and sleep disturbance (peak corrected p = 0.034) to predict advanced epigenetic age. 30872092

2019

dbSNP: rs9563121
rs9563121
KL
0.010 GeneticVariation BEFREE In gene by environment analyses, two KL variants (rs9315202 and rs9563121) interacted with PTSD severity (peak corrected p = 0.044) and sleep disturbance (peak corrected p = 0.034) to predict advanced epigenetic age. 30872092

2019

dbSNP: rs61816761
rs61816761
0.010 GeneticVariation BEFREE In multivariate prognostic models, persistent PSE (eczema at 1, 2 and 4 years of age) (odds ratio 0.27 (95% confidence interval 0.18-0.41)), PSE with sleep disturbance (due to itch at least once a week at 1, 2 and/or 4 years of age) (0.59 (0.43-0.81)), parental allergy (0.73 (0.55-0.96)), parental smoking at child's birth (0.70 (0.50-0.99)) and filaggrin mutation (R501X, R2447X, 2282del4) (0.47 (0.26-0.85)) were inversely associated with complete remission by school age. 29507996

2018

dbSNP: rs1212171
rs1212171
0.010 GeneticVariation BEFREE Genotype at the NTRK2 SNP rs1212171 was associated with both sleep disturbance and fatigue. 28205449

2017

dbSNP: rs1229030855
rs1229030855
0.010 GeneticVariation BEFREE Six missense changes were detected only in individuals with ASD with sleep disturbance: p.F498S in TIMELESS, p.S20R in NR1D1, p.R493C in PER3, p.H542R in CLOCK, p.L473S in ARNTL2, and p.A325V in MTNR1B. 25957987

2016

dbSNP: rs35275025
rs35275025
0.010 GeneticVariation BEFREE Six missense changes were detected only in individuals with ASD without sleep disturbance: p.S1241N in PER1, p.A325T in TIMELESS, p.S13T in ARNTL, p.G24E in MTNR1B, p.G24E in PER2, and p.T1177A in PER3. 25957987

2016

dbSNP: rs28933385
rs28933385
0.010 GeneticVariation BEFREE A missense mutation in codon 200 (E200K) of the PRNP was identified in this patient; CSF 14-3-3 protein was positive; sleep disturbance was the initial sign and the other symptoms gradually appeared, including memory loss, dizziness and ataxia. 20514992

2010

dbSNP: rs4719714
rs4719714
0.010 GeneticVariation BEFREE An evaluation was done on whether genetic variation in a prominent proinflammatory cytokine, interleukin-6 (IL-6 c.-6101A>T [rs4719714]), was associated with mean ratings of evening fatigue, morning fatigue, and sleep disturbance, as well as with the trajectories of these symptoms. 20570482

2010

dbSNP: rs767181086
rs767181086
0.010 GeneticVariation BEFREE A missense mutation in codon 200 (E200K) of the PRNP was identified in this patient; CSF 14-3-3 protein was positive; sleep disturbance was the initial sign and the other symptoms gradually appeared, including memory loss, dizziness and ataxia. 20514992

2010

dbSNP: rs1800629
rs1800629
TNF
0.010 GeneticVariation BEFREE In this study, we sought to determine whether a functional genetic variation in a prominent proinflammatory cytokine, tumor necrosis factor-alpha (TNFA-308G>A [rs1800629] promoter polymorphism) was associated with overall ratings of sleep disturbance and fatigue as well as with the trajectories of these symptoms. 19419979

2009