Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4148323
rs4148323
UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3
0.010 GeneticVariation BEFREE We found that rs12422149 of SLCO2B1, rs2032582_AT of ABCB1, rs2306283 of SLCO1B1 and rs4148323 of UGT1A1 exhibited a significant association with MMI-DILI; however, no significant difference existed after Bonferroni correction. 31240859

2019
dbSNP: rs4880
rs4880
SOD2
0.010 GeneticVariation BEFREE We have evaluated possible associations between the risk of developing DILI and common genetic variants of the manganese superoxide dismutase (SOD2 Val16Ala) and glutathione peroxidase (GPX1 Pro200Leu) genes, which are involved in mitochondrial oxidative stress management. 20578157

2010
dbSNP: rs1050450
rs1050450
GPX1
0.010 GeneticVariation BEFREE We have evaluated possible associations between the risk of developing DILI and common genetic variants of the manganese superoxide dismutase (SOD2 Val16Ala) and glutathione peroxidase (GPX1 Pro200Leu) genes, which are involved in mitochondrial oxidative stress management. 20578157

2010
dbSNP: rs4553808
rs4553808
CTLA4
0.010 GeneticVariation BEFREE We investigated the association of 5 CTLA4 single-nucleotide polymorphisms (SNPs) (rs733618 C/T, rs4553808 A/G, rs5742909 C/T, rs231775 A/G, and rs3087243 G/A) with drug-induced liver injury (DILI) in Chinese renal transplantation (RT) recipients. 23300559

2012
dbSNP: rs5742909
rs5742909
CTLA4
0.010 GeneticVariation BEFREE We investigated the association of 5 CTLA4 single-nucleotide polymorphisms (SNPs) (rs733618 C/T, rs4553808 A/G, rs5742909 C/T, rs231775 A/G, and rs3087243 G/A) with drug-induced liver injury (DILI) in Chinese renal transplantation (RT) recipients. 23300559

2012
dbSNP: rs3087243
rs3087243
CTLA4
0.010 GeneticVariation BEFREE We investigated the association of 5 CTLA4 single-nucleotide polymorphisms (SNPs) (rs733618 C/T, rs4553808 A/G, rs5742909 C/T, rs231775 A/G, and rs3087243 G/A) with drug-induced liver injury (DILI) in Chinese renal transplantation (RT) recipients. 23300559

2012
dbSNP: rs2741045
rs2741045
UGT1A10 ; UGT1A8 ; UGT1A9
0.010 GeneticVariation BEFREE We observed statistically significant associations between SNP rs2741045 and DILI at</span> both allele and genotype levels (allele: P=0.032; genotype: P=0.029; after Bonferroni correction). 25446781

2015