|
rs2032582
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The rs1799971 and rs1323040 polymorphisms of the <i>OPRM1</i> gene and rs2032582 and rs1128503 polymorphisms of the <i>ABCB1</i> gene are related to the analgesic effect and consumed dose of sufentanil in Chinese Han patients undergoing radical operation of lung cancer.
|
30455395 |
2019 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of MDR1 gene (C3435T) polymorphism and gene expression profiling in lung cancer patients treated with platinum-based chemotherapy.
|
26288241 |
2015 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Heterozygote carriers of SNPs in CYP1A2 1545T>C, -164C>A and -740T>G; CYP2A6 -47A>C; MDR1 3435T>C; NAT1 1088T>A and 1095A>C; GSTA2 S112T; GSTM3 V224I and MTHFR A222V had altered risk of developing lung cancer.
|
17259654 |
2007 |
|
rs2032582
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The current results taken together suggest that, aside from other known causes of lung cancer, such as tobacco smoke, the existence of polymorphisms in the ABCB1 gene and, specifically, the presence of the G2677T mutation can be crucial in conferring susceptibility to lung cancer.
|
17120199 |
2006 |
|
rs1128503
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1799971 and rs1323040 polymorphisms of the <i>OPRM1</i> gene and rs2032582 and rs1128503 polymorphisms of the <i>ABCB1</i> gene are related to the analgesic effect and consumed dose of sufentanil in Chinese Han patients undergoing radical operation of lung cancer.
|
30455395 |
2019 |
|
rs2235013
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Chemotherapy and stage jointly (p = 0.025) significantly modified the association between rs2235013 and survival, with statistically significant (p = 0.013, log-rank test) association observed in the subgroup of stage III to IV lung cancer patients who received chemotherapy as part of their first course of treatment (n = 160; 93.1% nonsmall cell).
|
25122423 |
2014 |
|
rs2188524
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotyping analyses for 6 common regulatory variants (reference single-nucleotide polymorphism 4728709 [rs4728709] and rs2188524 in the 5' flanking region of ABCB1 and rs3842 in its 3' untranslated region; rs3743527, rs212090, and rs212091 in the 3' untranslated region of ABCC1) was conducted in a case-control study of 500 patients with incident lung cancer and 517 cancer-free controls in a Chinese population.
|
19107762 |
2009 |
|
rs3842
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared with the wild adenosine/adenosine (A/A) genotype, the variant rs3842 genotype (adenosine/guanosine [A/G] + G/G) of ABCB1 was associated with a statistically significant increased risk of developing lung cancer (odds ratio [OR].
|
19107762 |
2009 |
|
rs149518139
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Heterozygote carriers of SNPs in CYP1A2 1545T>C, -164C>A and -740T>G; CYP2A6 -47A>C; MDR1 3435T>C; NAT1 1088T>A and 1095A>C; GSTA2 S112T; GSTM3 V224I and MTHFR A222V had altered risk of developing lung cancer.
|
17259654 |
2007 |