Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1024611
rs1024611
0.010 GeneticVariation BEFREE GG genotype of rs1</span>024611 was significantly correlated with higher epidermal thickness and lower dermis thickness in patients with DFUs (P < .01). 29995756

2018

dbSNP: rs13207351
rs13207351
0.010 GeneticVariation BEFREE But no significant differences were detected in rs13207351 genotype and allele distributions between patients and control groups (P > .05).Individuals carrying VEGF rs699947 A allele show low susceptibility to DFU in the Chinese Han population. 29768333

2018

dbSNP: rs1800629
rs1800629
TNF
0.010 GeneticVariation BEFREE The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU). 30009916

2018

dbSNP: rs1800795
rs1800795
0.010 GeneticVariation BEFREE The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU). 30009916

2018

dbSNP: rs1801157
rs1801157
0.010 GeneticVariation BEFREE The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU). 30009916

2018

dbSNP: rs361525
rs361525
TNF
0.010 GeneticVariation BEFREE The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU). 30009916

2018

dbSNP: rs699947
rs699947
0.010 GeneticVariation BEFREE But no significant differences were detected in rs13207351 genotype and allele distributions between patients and control groups (P > .05).Individuals carrying VEGF rs699947 A allele show low susceptibility to DFU in the Chinese Han population. 29768333

2018

dbSNP: rs1800449
rs1800449
LOX
0.010 GeneticVariation BEFREE Our finding predicts that there is an association of LOX gene polymorphism (G473A) on diabetes and DFU patients when compared to that of healthy controls. 28522400

2017

dbSNP: rs11549465
rs11549465
0.010 GeneticVariation BEFREE Impact of the hypoxia inducible factor-1α (HIF-1α) pro582ser polymorphism and its gene expression on diabetic foot ulcers. 26113285

2015

dbSNP: rs10759931
rs10759931
0.010 GeneticVariation BEFREE The objective of the present work was to evaluate the association of TLR4 single nucleotide polymorphisms (SNPs) rs4986790, rs4986791, rs11536858 (merged into rs10759931), rs1927911, and rs1927914 with increased diabetic foot ulcer (DFU) risk in patients with type 2 diabetes mellitus (T2DM). 23936790

2013

dbSNP: rs11536858
rs11536858
0.010 GeneticVariation BEFREE The objective of the present work was to evaluate the association of TLR4 single nucleotide polymorphisms (SNPs) rs4986790, rs4986791, rs11536858 (merged into rs10759931), rs1927911, and rs1927914 with increased diabetic foot ulcer (DFU) risk in patients with type 2 diabetes mellitus (T2DM). 23936790

2013

dbSNP: rs1927911
rs1927911
0.010 GeneticVariation BEFREE The objective of the present work was to evaluate the association of TLR4 single nucleotide polymorphisms (SNPs) rs4986790, rs4986791, rs11536858 (merged into rs10759931), rs1927911, and rs1927914 with increased diabetic foot ulcer (DFU) risk in patients with type 2 diabetes mellitus (T2DM). 23936790

2013

dbSNP: rs1927914
rs1927914
0.010 GeneticVariation BEFREE Risk genotypes of all SNPs except rs1927914 were significantly associated with DFU. 23936790

2013

dbSNP: rs3918242
rs3918242
0.010 GeneticVariation BEFREE Here, we aim to investigate that whether single nucleotide polymorphism (SNP -1562C>T) (rs3918242) in the promoter region of MMP-9 gene, which alters the transcriptional activity of MMP-9 is associated with type 2 diabetes and diabetic foot ulcers (DFUs). 24043671

2013

dbSNP: rs4986791
rs4986791
0.010 GeneticVariation BEFREE The objective of the present work was to evaluate the association of TLR4 single nucleotide polymorphisms (SNPs) rs4986790, rs4986791, rs11536858 (merged into rs10759931), rs1927911, and rs1927914 with increased diabetic foot ulcer (DFU) risk in patients with type 2 diabetes mellitus (T2DM). 23936790

2013

dbSNP: rs7903146
rs7903146
0.010 GeneticVariation BEFREE In the present study, a positive significant association between DFU and the TT genotype of rs7903146 (C/T) variant of TCF7L2 gene was found. 24214952

2013

dbSNP: rs1799971
rs1799971
0.010 GeneticVariation BEFREE The A118G polymorphism of mu-opioid receptor may be closely associated with DFU pain in 34 out of 50 patients in the painless group and in 5 out of 15 patients in the painful group. 19303332

2010