Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs41297579
rs41297579
0.010 GeneticVariation BEFREE rs9313422 G>C and rs41297579 G>A polymorphisms in the promoter region of TIM-1 could increase the risk of CAP in children and showed a relation with inflammatory responses and severity. 31800133

2020

dbSNP: rs9313422
rs9313422
0.010 GeneticVariation BEFREE rs9313422 G>C and rs41297579 G>A polymorphisms in the promoter region of TIM-1 could increase the risk of CAP in children and showed a relation with inflammatory responses and severity. 31800133

2020

dbSNP: rs1045411
rs1045411
0.010 GeneticVariation BEFREE There was no correlation between the HMGB1 rs1045411 SNP alleles and CAP or SCAP (p > 0.05). 30562142

2019

dbSNP: rs1412125
rs1412125
0.010 GeneticVariation BEFREE The risk of CAP was higher in carriers of the mutant HMGB1 rs1412125 and rs2249825 alleles than those that had the wild type alleles (adjusted odds ratio [OR] = 1.241; 95% confidence interval [CI] = 1.061-1.448; p = 0.007; adjusted OR = 1.225; 95% CI = 1.038-1.427; p = 0.016, respectively). 30562142

2019

dbSNP: rs2249825
rs2249825
0.010 GeneticVariation BEFREE The risk of CAP was higher in carriers of the mutant HMGB1 rs1412125 and rs2249825 alleles than those that had the wild type alleles (adjusted odds ratio [OR] = 1.241; 95% confidence interval [CI] = 1.061-1.448; p = 0.007; adjusted OR = 1.225; 95% CI = 1.038-1.427; p = 0.016, respectively). 30562142

2019

dbSNP: rs10954213
rs10954213
0.010 GeneticVariation BEFREE In this study, we investigated the effects of four IFR5 variants, rs77571059, rs2004640, rs10954213, and rs3807306 on the susceptibility to CAP by genotyping 228 CAP patients and 177 healthy donors. 30176312

2018

dbSNP: rs2004640
rs2004640
0.010 GeneticVariation BEFREE Our results indicated that IFR5 variants rs77571059 and rs2004640 and haplotype GTAA were associated with the susceptibility to CAP and rs77571059 was related to the severity of the disease, suggesting that IFR5 variants may contribute to the pathogenesis of CAP and may serve as prognostic markers of CAP susceptibility and outcome. 30176312

2018

dbSNP: rs2228570
rs2228570
VDR
0.010 GeneticVariation BEFREE The VDR gene Fok I (rs2228570) polymorphism confers susceptibility to CAP in Egyptian children. 30135595

2018

dbSNP: rs3807306
rs3807306
0.010 GeneticVariation BEFREE In this study, we investigated the effects of four IFR5 variants, rs77571059, rs2004640, rs10954213, and rs3807306 on the susceptibility to CAP by genotyping 228 CAP patients and 177 healthy donors. 30176312

2018

dbSNP: rs77571059
rs77571059
0.010 GeneticVariation BEFREE In this study, we investigated the effects of four IFR5 variants, rs77571059, rs2004640, rs10954213, and rs3807306 on the susceptibility to CAP by</span> genotyping 228 CAP patients and 177 healthy donors. 30176312

2018

dbSNP: rs1205
rs1205
CRP
0.010 GeneticVariation BEFREE The CRP +1846C/T (rs1205), IL-6 -597G/A (rs1800797), and IL-10 -592C/A (rs1800872) may be associated with the susceptibility and severity of CAP. 27705004

2016

dbSNP: rs16944
rs16944
0.010 GeneticVariation BEFREE We studied common polymorphisms in the genes of proinflammatory cytokines (IL6 rs1800795, IL8 rs4073, IL1B rs16944), anti-inflammatory cytokines (IL10 rs1800896, IL4 rs2243250, IL13 rs20541) and toll-like receptors (TLR2 rs5743708 and rs4696480, TLR4 rs4986791, TLR9 rs352139, rs5743836 and rs187084) in patients with community-acquired pneumonia (CAP) (390 cases, 203 controls) and nosocomial pneumonia (355 cases, 216 controls). 27725770

2016

dbSNP: rs1800797
rs1800797
0.010 GeneticVariation BEFREE The CRP +1846C/T (rs1205), IL-6 -597G/A (rs1800797), and IL-10 -592C/A (rs1800872) may be associated with the susceptibility and severity of CAP. 27705004

2016

dbSNP: rs1800872
rs1800872
0.010 GeneticVariation BEFREE The CRP +1846C/T (rs1205), IL-6 -597G/A (rs1800797), and IL-10 -592C/A (rs1800872) may be associated with the susceptibility and severity of CAP. 27705004

2016

dbSNP: rs187084
rs187084
0.010 GeneticVariation BEFREE We studied common polymorphisms in the genes of proinflammatory cytokines (IL6 rs1800795, IL8 rs4073, IL1B rs16944), anti-inflammatory cytokines (IL10 rs1800896, IL4 rs2243250, IL13 rs20541) and toll-like receptors (TLR2 rs5743708 and rs4696480, TLR4 rs4986791, TLR9 rs352139, rs5743836 and rs187084) in patients with community-acquired pneumonia (CAP) (390 cases, 203 controls) and nosocomial pneumonia (355 cases, 216 controls). 27725770

2016

dbSNP: rs20541
rs20541
0.010 GeneticVariation BEFREE We studied common polymorphisms in the genes of proinflammatory cytokines (IL6 rs1800795, IL8 rs4073, IL1B rs16944), anti-inflammatory cytokines (IL10 rs1800896, IL4 rs2243250, IL13 rs20541) and toll-like receptors (TLR2 rs5743708 and rs4696480, TLR4 rs4986791, TLR9 rs352139, rs5743836 and rs187084) in patients with community-acquired pneumonia (CAP) (390 cases, 203 controls) and nosocomial pneumonia (355 cases, 216 controls). 27725770

2016

dbSNP: rs2243250
rs2243250
IL4
0.010 GeneticVariation BEFREE We studied common polymorphisms in the genes of proinflammatory cytokines (IL6 rs1800795, IL8 rs4073, IL1B rs16944), anti-inflammatory cytokines (IL10 rs1800896, IL4 rs2243250, IL13 rs20541) and toll-like receptors (TLR2 rs5743708 and rs4696480, TLR4 rs4986791, TLR9 rs352139, rs5743836 and rs187084) in patients with community-acquired pneumonia (CAP) (390 cases, 203 controls) and nosocomial pneumonia (355 cases, 216 controls). 27725770

2016

dbSNP: rs4073
rs4073
0.010 GeneticVariation BEFREE We studied common polymorphisms in the genes of proinflammatory cytokines (IL6 rs1800795, IL8 rs4073, IL1B rs16944), anti-inflammatory cytokines (IL10 rs1800896, IL4 rs2243250, IL13 rs20541) and toll-like receptors (TLR2 rs5743708 and rs4696480, TLR4 rs4986791, TLR9 rs352139, rs5743836 and rs187084) in patients with community-acquired pneumonia (CAP) (390 cases, 203 controls) and nosocomial pneumonia (355 cases, 216 controls). 27725770

2016

dbSNP: rs5743708
rs5743708
0.010 GeneticVariation BEFREE TLR2 rs5743708 minor genotype appeared to be associated with CAP/Legionnaires' disease/pneumococcal disease. 27725770

2016

dbSNP: rs2239185
rs2239185
VDR
0.010 GeneticVariation BEFREE TT genotype of rs2239185 in VDR gene might be one of the potential genetic risk factors for CAP, and T allele of rs2239185 might be associated with the susceptibility to CAP and the severity of CAP. 25367052

2015

dbSNP: rs7096206
rs7096206
0.010 GeneticVariation BEFREE We genotyped and analyzed 4 important MBL2 single nucleotide polymorphisms (SNPs; rs5030737, rs1800450, rs1800451, and rs7096206) in 1839 European community-acquired pneumonia (CAP) and peritonitis sepsis cases, and 477 controls from the United Kingdom. 25969530

2015

dbSNP: rs1801282
rs1801282
0.010 GeneticVariation BEFREE Carotid artery plaque (CAP) and carotid intima-media thickness (CIMT) in HD patients with CT + TT or Pro12Ala genotypes were also less than that in patients with CCor Pro12Pro genotypes, respectively. 25096510

2014

dbSNP: rs1805192
rs1805192
0.010 GeneticVariation BEFREE Carotid artery plaque (CAP) and carotid intima-media thickness (CIMT) in HD patients with CT + TT or Pro12Ala genotypes were also less than that in patients with CCor Pro12Pro genotypes, respectively. 25096510

2014

dbSNP: rs2606345
rs2606345
0.010 GeneticVariation BEFREE Individual single nucleotide polymorphism (SNP) analysis revealed a strong association between CYP1A1 rs2606345 and CAP (p=3.9 × 10(-5), odds ratio (OR) 0.42, 95% confidence interval (CI) 0.27-0.63). 23411129

2013

dbSNP: rs4898
rs4898
0.010 GeneticVariation BEFREE No significant difference was found in the genotype distribution of TIMP-1 372C/T between patients with CAP and normal controls. 23792071

2013