Gene: F11 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2036914
rs2036914
F11
C 0.830 GeneticVariation GWASCAT Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. 31420334

2019
dbSNP: rs2036914
rs2036914
F11
0.830 GeneticVariation BEFREE Our findings suggest that the risk of VTE by FHMI is not explained by rs8176719 (ABO), rs6025 (F5), rs1799963 (F2), rs2066865 (FGG), and rs2036914 (F11). 31124268

2019
dbSNP: rs2036914
rs2036914
F11
0.830 GeneticVariation BEFREE The meta-analysis revealed that the F11 rs2289252, F11 rs2036914, FGG rs2066865, and CYP4V2 rs13146272 polymorphisms were closely related to the development of VTE in the white race under the best genetic models after multiple testing adjustments. 28353616

2017
dbSNP: rs2036914
rs2036914
F11
0.830 GeneticVariation BEFREE In F11, the CC genotype for rs2036914 and the CT and TT genotypes for rs2289252 were associated with a significantly higher VTE risk. 23150947

2013
dbSNP: rs2036914
rs2036914
F11
0.830 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494

2011
dbSNP: rs3756008
rs3756008
F11
0.810 GeneticVariation BEFREE A nucleotide variant (rs3756008) in the promoter region of the FXI gene was recently reported for association with venous thromboembolism. 24420855

2014
dbSNP: rs3756008
rs3756008
F11
0.810 GeneticVariation GWASDB A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. 22672568

2012
dbSNP: rs3756008
rs3756008
F11
T 0.810 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494

2011
dbSNP: rs3756008
rs3756008
F11
T 0.810 GeneticVariation GWASCAT Genetics of venous thrombosis: insights from a new genome wide association study. 21980494

2011
dbSNP: rs4253417
rs4253417
F11
C 0.800 GeneticVariation GWASCAT Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. 31676865

2019
dbSNP: rs4253417
rs4253417
F11
C 0.800 GeneticVariation GWASCAT Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism. 25772935

2015
dbSNP: rs4253399
rs4253399
F11
G 0.800 GeneticVariation GWASDB A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 23650146

2013
dbSNP: rs4253399
rs4253399
F11
G 0.800 GeneticVariation GWASCAT A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. 23650146

2013
dbSNP: rs4253399
rs4253399
F11
0.800 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494

2011
dbSNP: rs4253417
rs4253417
F11
0.800 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494

2011
dbSNP: rs2289252
rs2289252
F11 ; F11-AS1
T 0.740 GeneticVariation GWASCAT Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. 31420334

2019
dbSNP: rs2289252
rs2289252
F11 ; F11-AS1
0.740 GeneticVariation BEFREE The meta-analysis revealed that the F11 rs2289252, F11 rs2036914, FGG rs2066865, and CYP4V2 rs13146272 polymorphisms were closely related to the development of VTE in the white race under the best genetic models after multiple testing adjustments. 28353616

2017
dbSNP: rs2289252
rs2289252
F11 ; F11-AS1
0.740 GeneticVariation BEFREE In conclusion, F5 rs6025 and F11 rs2289252 contributed to the risk of recurrent VTE and the combination is of potential clinical relevance for risk prediction. 26423325

2016
dbSNP: rs2289252
rs2289252
F11 ; F11-AS1
0.740 GeneticVariation BEFREE Seven SNPs (F5 rs6025, F2 rs1799963, ABO rs514659, FGG rs2066865, F11 rs2289252, PROC rs1799810 and KNG1 rs710446) with four SNP-SNP interactions contributed to the genetic risk score for VTE, with an AUC of 0.66 (95% CI, 0.64-0.68). 25472531

2015
dbSNP: rs2289252
rs2289252
F11 ; F11-AS1
0.740 GeneticVariation BEFREE In F11, the CC genotype for rs2036914 and the CT and TT genotypes for rs2289252 were associated with a significantly higher VTE risk. 23150947

2013
dbSNP: rs925451
rs925451
F11
0.710 GeneticVariation GWASDB A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. 22672568

2012
dbSNP: rs925451
rs925451
F11
0.710 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494

2011
dbSNP: rs925451
rs925451
F11
0.710 GeneticVariation BEFREE After Bonferroni adjustment, four single nucleotide polymorphisms (SNPs) were significantly associated with VTE: Factor XI rs925451 polymorphism, factor XI rs2289252 polymorphism, factor II rs1799963 (G20210A) polymorphism and factor V Leiden rs6025. 20352152

2010
dbSNP: rs4253421
rs4253421
F11
G 0.700 GeneticVariation GWASCAT Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism. 31420334

2019
dbSNP: rs4253416
rs4253416
F11
T 0.700 GeneticVariation GWASCAT Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor. 28373160

2017