|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results demonstrate the high frequency of C allele of ABCB1 T3435C in B-CLL patients with Kurdish ethnicity.
|
25586345 |
2015 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Taken together, these data indicate that the MDR1 C3435T SNP may carry an increased risk of developing B-CLL, possibly by virtue of decreased protection against P-gp-substrate carcinogens.
|
17085864 |
2007 |
|
rs956572
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In humans, a single-nucleotide polymorphism in the B-cell chronic lymphocytic leukemia/lymphoma-2 (Bcl-2) gene, rs956572, has been found to significantly modulate Bcl-2 protein expression in the brain.
|
29422088 |
2018 |
|
rs10434
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that the A allele and the AA genotype of rs10434 were more frequent in B-CLL patients than in control subjects (0.54 vs 0.34; 27 vs 13%; respectively).
|
25966180 |
2015 |
|
rs3803800
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although the obtained P-values for all 20 SNPs did not reach statistical significance for this study (α = 0.003), the high value of the global chi-squared statistic (χ(2) df = 38 = 52.65; P = 0.0586), and obtained values of odds ratio indicate that rs9514828 (BAFF), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of B-CLL.
|
26268376 |
2015 |
|
rs4985726
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although the obtained P-values for all 20 SNPs did not reach statistical significance for this study (α = 0.003), the high value of the global chi-squared statistic (χ(2) df = 38 = 52.65; P = 0.0586), and obtained values of odds ratio indicate that rs9514828 (BAFF), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of B-CLL.
|
26268376 |
2015 |
|
rs9514828
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although the obtained P-values for all 20 SNPs did not reach statistical significance for this study (α = 0.003), the high value of the global chi-squared statistic (χ(2) df = 38 = 52.65; P = 0.0586), and obtained values of odds ratio indicate that rs9514828 (BAFF), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of B-CLL.
|
26268376 |
2015 |
|
rs77375493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In 4 previously reported patients with JAK2(V617F)-positive Ph(-) MPN and B-CLL there was no definitive proof of JAK2(V617F) mutation in B-CLL cells, although this was suggested in 1 patient.
|
22890406 |
2012 |
|
rs1800561
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results were confirmed in study B, which showed an association between</span> B</span>-CLL and genotypes rs6449182 CG (OR, 4.00; 95% CI, 2.7-6.0), rs6449182 GG (OR, 12.84; 95% CI, 4.3-38.7), and rs1800561 CT (OR, 10.12; 95% CI, 1.3-81.6), and in the combined analysis of both studies.
|
19240243 |
2009 |
|
rs6449182
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results were confirmed in study B, which showed an association between B</span>-CLL and genotypes rs6449</span>182 CG (OR, 4.00; 95% CI, 2.7-6.0), rs6449182 GG (OR, 12.84; 95% CI, 4.3-38.7), and rs1800561 CT (OR, 10.12; 95% CI, 1.3-81.6), and in the combined analysis of both studies.
|
19240243 |
2009 |
|
rs1373425060
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Anti-ZAP-70 moAb clone 17A/P-ZAP70 gave elevated results for all B-CLL patients as well as healthy controls.
|
16906577 |
2006 |
|
rs758272654
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we show that the GNAS1 T393C status is a novel independent prognostic marker in patients with B-CLL.
|
17020971 |
2006 |
|
rs1057519695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs1057519834
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs11554290
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs121913237
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs121913240
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs121913250
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs121913529
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs121913530
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |