|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We evaluated the associations of <i>miR-499A</i>>G (rs3746444), <i>miR-149C</i>>T (rs2292832), <i>miR-196a2T</i>>C (rs11614913), and <i>miR-146aG</i>>C (rs2910164) with HCC susceptibility in 100 HCC patients (70 males and 30 females) and 120 healthy controls (70 males and 50 females), using the PCR-restriction fragment length polymorphism method.
|
30215231 |
2019 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There was significant difference in miR-499 (rs3746444) genotypes frequency between the three studied groups as the GG genotype was significantly lower in HCC cases than other groups (P = 0.009) while the combined miR-499 (AA+AG) genotypes were significantly higher in HCC cases than other groups (P = 0.005).
|
31759375 |
2019 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This meta-analysis suggested that mir-499 rs3746444 polymorphism was associated with an increased HCC risk.
|
29970712 |
2018 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Subgroup analysis based on type of tumor was also performed, miR-499 rs3746444 is associated with susceptibility of cervical squamous cell carcinoma, lung cancer, prostate cancer, and hepatocellular carcinoma.
|
29946268 |
2018 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To evaluate the association between four common miRNAs (miR-146a rs2910164; miR-149 rs2292832; miR-196a2 rs11614913 and miR-499 rs3746444) and HCC risk, an updated meta-analysis was performed.
|
28499985 |
2017 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis of the relationship between microRNA-499 rs3746444 polymorphism and hepatocellular carcinoma risk in Asians.
|
27461631 |
2017 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the Asian population, miR-499 rs3746444 polymorphism was associated with a decreased risk of HCC in recessive models.
|
28188097 |
2017 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study suggested that miR-499 rs3746444 might play an important role in the development o</span>f HCC.
|
27453271 |
2016 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MiR-196a2 rs11614913 and miR-499a rs3746444 were significantly associated with a curative effect and a positive prognosis of TACE for primary HCC.
|
27525669 |
2016 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Predictive role of miR-146a rs2910164 (C>G), miR-149 rs2292832 (T>C), miR-196a2 rs11614913 (T>C) and miR-499 rs3746444 (T>C) in the development of hepatocellular carcinoma.
|
26823863 |
2015 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
No significant association was found between miR-499 rs3746444 and HCC, but subgroup study showed that subjects with CC genotype are more vulnerable to HCC than TT genotype in the Chinese population.
|
25108400 |
2014 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results indicate that people who carry the rs3746444 CT or CC genotypes may have a significantly increased susceptibility to hepatocellular carcinoma (adjusted odds ratio [AOR] = 2.84, 95% confidence interval [CI] = 1.88-4.30).
|
24587132 |
2014 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
rs3746444 polymorphism and susceptibility to hepatocellular carcinoma: evidence from published studies.
|
25074528 |
2014 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
miR-499 rs3746444 may contribute to the risk and prognosis of HCC, indicating that this SNP could be developed as a biomarker for HCC prediction.
|
24854593 |
2014 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The high-resolution melting (HRM) analysis was used to determine whether the occurrence of the SNPs of miR-146a C > G (rs2910164), miR-196a2 C > T (rs11614913), miR-301b A > G (rs384262), and miR-499 C > T (rs3746444) differs in frequency-matched 314 HCC patients and 407 controls by age and sex.
|
25176041 |
2014 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, the MiR-499A>G rs3746444 polymorphism is associated with HCC risk in the Chinese population, and may be useful predictive marker for CAD susceptibility.
|
23679271 |
2013 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We did not find a significant association of miR-146aG>C rs2910164 and miR-499A>G rs3746444 polymorphisms with hepatocellular carcinoma risk in the Chinese population.
|
24301908 |
2013 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that miR-146a rs2910164 and miR-499 rs3746444 polymorphisms may not be associated with the risk of HCC, especially for Asian population.
|
23437296 |
2013 |
|
rs3746444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
No statistically significant differences were found in the allele or genotype distributions of the miR-499 rs3746444 polymorphism among HCC and cancer-free control subjects (P>0.05).
|
22393998 |
2011 |