|
rs4444903
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) near the epidermal growth factor (EGF) (rs4444903), IL28B (rs12979860), and PNPLA3 (rs738409) loci are associated with treatment response, fibrosis, and hepatocellular carcinoma in non-transplant hepatitis C, but allograft population data are limited.
|
26854475 |
2016 |
|
rs4444903
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The association between epidermal growth factor (EGF) gene +61A/G polymorphism (rs4444903) and hepatocellular carcinoma (HCC) susceptibility has been widely reported, but the results were inconsistent.
|
25927412 |
2015 |
|
rs4444903
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) in the epidermal growth factor (EGF, rs4444903), patatin-like phospholipase domain-containing protein 3 (PNPLA3, rs738409) genes, and near the interleukin-28B (IL28B, rs12979860) gene are linked to treatment response, fibrosis, and hepatocellular carcinoma (HCC) in chronic hepatitis C. Whether these SNPs independently or in combination predict clinical deterioration in hepatitis C virus (HCV)-related cirrhosis is unknown.
|
25504078 |
2014 |
|
rs4444903
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Additionally, the haplotype T-G constructed by rs11569017 and rs4444903 of the EGF gene might increase the risk of HBV-related HCC (p=0.002, OR=1.44, 95% CI=1.15-1.82).
|
23790025 |
2013 |
|
rs4444903
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Previous work suggests an association between the EGF 61*A/G polymorphism (rs4444903) and susceptibility to hepatocellular carcinoma (HCC), but the results have been inconsistent.
|
22403631 |
2012 |
|
rs4444903
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism 61*G (rs4444903) in the epidermal growth factor (EGF) gene has been associated, in 2 case-control studies, with hepatocellular carcinoma (HCC).
|
21440548 |
2011 |
|
rs1336242054
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of wild-type Shp2 and SUMOylation-defective Shp2(K590R) mutant reveals that SUMOylation of Shp2 promotes EGF-stimulated ERK signaling pathway and increases anchorage-independent cell growth and xenografted tumor growth of hepatocellular carcinoma (HCC) cell lines.
|
25823821 |
2015 |
|
rs11569017
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs11569017 T allele was associated with susceptibility to HBV-related HCC.
|
23790025 |
2013 |