rs1053004
|
|
|
0.040 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> The meta-analysis showed that <i>STAT3</i> rs1053004 polymorphism may be the risk for developing chronic HBV infection but not associated with HCC.
|
31160486 |
2019 |
rs1053004
|
|
|
0.040 |
GeneticVariation |
BEFREE |
These results illustrate that perhaps rs1053004 polymorphisms in the STAT3 gene participated in the progression of hepatitis B to HCC in Iranian people.
|
29307341 |
2017 |
rs1053004
|
|
|
0.040 |
GeneticVariation |
BEFREE |
These findings suggest that the SNP rs1053004 in STAT3 might contribute to HCC susceptibility and could be used as a genetic marker for HCC in the Thai population.
|
26163643 |
2015 |
rs1053004
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In multivariate regression analyses, multiplicative interaction of rs1053004 with T1674C/G significantly increased HCC risk, whereas rs2293152 and A1726C interaction reduced it, adjusting for covariates including HBV mutations in the enhancer II/basal core promoter/precore region; the interaction of rs4796793 with preS2 start codon mutation significantly increased HCC risk, adjusting for covariates including HBV mutations in the preS region.
|
23386590 |
2013 |
rs2293152
|
|
|
0.020 |
GeneticVariation |
BEFREE |
However, no significant association between rs2293152 and HCC development was observed.
|
26745093 |
2015 |
rs2293152
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In multivariate regression analyses, multiplicative interaction of rs1053004 with T1674C/G significantly increased HCC risk, whereas rs2293152 and A1726C interaction reduced it, adjusting for covariates including HBV mutations in the enhancer II/basal core promoter/precore region; the interaction of rs4796793 with preS2 start codon mutation significantly increased HCC risk, adjusting for covariates including HBV mutations in the preS region.
|
23386590 |
2013 |
rs111904020
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our findings have shown that the SNP rs111904020 (U/G) in STAT3 3'UTR acted as promotion factors in the HCC development through disrupting the regulatory role of miR-214 in STAT3 expression.
|
27619679 |
2016 |
rs4796793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate regression analyses, multiplicative interaction of rs1053004 with T1674C/G significantly increased HCC risk, whereas rs2293152 and A1726C interaction reduced it, adjusting for covariates including HBV mutations in the enhancer II/basal core promoter/precore region; the interaction of rs4796793 with preS2 start codon mutation significantly increased HCC risk, adjusting for covariates including HBV mutations in the preS region.
|
23386590 |
2013 |