Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042571
rs1042571
POMC
0.010 GeneticVariation BEFREE AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018). 24831852

2014
dbSNP: rs1049353
rs1049353
CNR1
0.010 GeneticVariation BEFREE Present findings show for the first time that the CNR1 1359 G/A SNP and the FAAH cDNA 385C to A SNP are significantly associated to anorexia nervosa and bulimia nervosa, and demonstrate a synergistic effect of the two SNPs in anorexia nervosa. 19659925

2009
dbSNP: rs12490016
rs12490016
LINC00880 ; LINC00881
0.010 GeneticVariation BEFREE Three of the GWS loci identified (rs200889048, rs12490016 and rs1630623) were not previously reported by GWAS of BMI in the general population, and two of them raise interesting hypotheses: rs12490016-a regulatory variant located within LINC00880, where there are other GWAS-identified variants associated with birth size, adiposity in newborns and bulimia symptoms, which also interact with social stress in relation to birth size; rs1630623-a regulatory variant related to ALDH1A1, a gene involved in alcohol metabolism and adipocyte plasticity. 26458734

2017
dbSNP: rs13338499
rs13338499
LOC101927837
0.010 GeneticVariation BEFREE AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018). 24831852

2014
dbSNP: rs142014203
rs142014203
NKAIN3
T 0.800 GeneticVariation GWASCAT Genetic variants associated with disordered eating. 23568457

2013
dbSNP: rs142014203
rs142014203
NKAIN3
T 0.800 GeneticVariation GWASDB Genetic variants associated with disordered eating. 23568457

2013
dbSNP: rs1445130
rs1445130
LOC105373456
A 0.800 GeneticVariation GWASDB Genetic variants associated with disordered eating. 23568457

2013
dbSNP: rs1445130
rs1445130
LOC105373456
A 0.800 GeneticVariation GWASCAT Genetic variants associated with disordered eating. 23568457

2013
dbSNP: rs1630623
rs1630623
TMC1
0.010 GeneticVariation BEFREE Three of the GWS loci identified (rs200889048, rs12490016 and rs1630623) were not previously reported by GWAS of BMI in the general population, and two of them raise interesting hypotheses: rs12490016-a regulatory variant located within LINC00880, where there are other GWAS-identified variants associated with birth size, adiposity in newborns and bulimia symptoms, which also interact with social stress in relation to birth size; rs1630623-a regulatory variant related to ALDH1A1, a gene involved in alcohol metabolism and adipocyte plasticity. 26458734

2017
dbSNP: rs1800497
rs1800497
ANKK1
0.010 GeneticVariation BEFREE We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. 22683321

2012
dbSNP: rs200889048
rs200889048 		0.010 GeneticVariation BEFREE Three of the GWS loci identified (rs200889048, rs12490016 and rs1630623) were not previously reported by GWAS of BMI in the general population, and two of them raise interesting hypotheses: rs12490016-a regulatory variant located within LINC00880, where there are other GWAS-identified variants associated with birth size, adiposity in newborns and bulimia symptoms, which also interact with social stress in relation to birth size; rs1630623-a regulatory variant related to ALDH1A1, a gene involved in alcohol metabolism and adipocyte plasticity. 26458734

2017
dbSNP: rs287103
rs287103
KCTD15
0.010 GeneticVariation BEFREE The <i>KCTD15</i> rs287103 T variant allele was associated with increased risk of bulimia nervosa (BN) (OR = 4.34 [1.47-29.52]; <i>p</i> = .003) and with scores of psychopathological scales of these patients. 28948079

2017
dbSNP: rs4633
rs4633
COMT ; MIR4761
0.010 GeneticVariation BEFREE This study aimed to (1) examine if certain variants of the COMT genetic markers (rs6269, rs4633, rs4818 and rs4680) are more common in BN versus controls; (2) assess transmission of COMT alleles in BN families; and (3) explore the role of COMT genotypes and haplotypes in bulimic women with childhood ADHD history. 21300128

2011
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa. 21300128

2011
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE There were no significant group differences in COMT Val158Met alleles and genotype frequencies between patients and controls, for all EDs pooled together [range of odds ratios (ORs): 0.96-1.04, p-values: 0.46-0.97, I<sup>2</sup>  = 0%] and when analysing separately patients with AN (ORs: 0.94-1.04, p-values: 0.31-0.61, I<sup>2</sup>  = 0%) or BN (ORs: 0.80-1.09, p-values: 0.28-0.64, I<sup>2</sup>  = 0-44%). 29057600

2017
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. 22683321

2012
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE Previous studies have shown that the met allele of the COMT val158met single nucleotide polymorphism (SNP) is associated with Bulimia Nervosa (BN). 25216558

2014
dbSNP: rs4818
rs4818
COMT ; MIR4761
0.010 GeneticVariation BEFREE This study aimed to (1) examine if certain variants of the COMT genetic markers (rs6269, rs4633, rs4818 and rs4680) are more common in BN versus controls; (2) assess transmission of COMT alleles in BN families; and (3) explore the role of COMT genotypes and haplotypes in bulimic women with childhood ADHD history. 21300128

2011
dbSNP: rs495225
rs495225
GHSR
0.010 GeneticVariation BEFREE Therefore, the CC type of GHSR gene polymorphism (171T/C) is a risk factor for BN, but not for AN. 16362631

2006
dbSNP: rs52820871
rs52820871
MC4R
0.010 GeneticVariation BEFREE In the obesity group, 10 different variants were identified, whereas in the binge-eating patients, only two individuals with bulimia nervosa were found to carry the I251L polymorphism, which did not correlate with weight, BMI, or psychopathological features. 25419636

2015
dbSNP: rs53576
rs53576
CAV3 ; OXTR
0.010 GeneticVariation BEFREE We found a positive association between the G allele of OXTR rs53576 and BN. 25773927

2015
dbSNP: rs554073050
rs554073050
CCK
0.010 GeneticVariation BEFREE Therefore, the CC type of GHSR gene polymorphism (171T/C) is a risk factor for BN, but not for AN. 16362631

2006
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.020 GeneticVariation BEFREE In both BN and BED groups, subjects carrying the 196A/A genotype exhibited a weekly frequency of bingeing and a severity of binge eating (as assessed by the Bulimia Investigation Test Edinburgh) significantly higher than those with the 196A/G and 196G/G genotypes. 16901635

2006
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.020 GeneticVariation BEFREE Some studies have shown association of BDNF -270C/T single-nucleotide polymorphism (SNP) with bulimia nervosa (BN), while BDNF Val66Met variant has been shown to be associated with both BN and anorexia nervosa (AN). 17376155

2007
dbSNP: rs6296
rs6296
HTR1B ; LOC105377864
0.020 GeneticVariation BEFREE Ninety-eight women with BN were genotyped based on the G861C polymorphism of the serotonin-1B receptor gene (HTR1B). 11690602

2001