|
rs10490924
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Six single nucleotide polymorphisms-rs10490924 (ARMS2), rs1061170 (CFH), rs2230199 (C3), rs116503776 and rs114254831 (C2/CFB), and rs943080 (VEGF-A)-and the genetic risk score (GRS) were assessed for association with RPD.
|
31558345 |
2019 |
|
rs1061170
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Six single nucleotide polymorphisms-rs10490924 (ARMS2), rs1061170 (CFH), rs2230199 (C3), rs116503776 and rs114254831 (C2/CFB), and rs943080 (VEGF-A)-and the genetic risk score (GRS) were assessed for association with RPD.
|
31558345 |
2019 |
|
rs10490924
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Comparison of above-mentioned ORs revealed statistically higher values for GT and TT genotypes of ARMS2 A69S compared with CFH Y402H genotypes (p = 0.011, p = 0.014, respectively).Our analysis showed stronger contribution of ARMS2 in AMD with RPD group versus AMD without RPD group, in comparison with CFH genotypes.
|
28593728 |
2018 |
|
rs1061170
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Comparison of above-mentioned ORs revealed statistically higher values for GT and TT genotypes of ARMS2 A69S compared with CFH Y402H genotypes (p = 0.011, p = 0.014, respectively).Our analysis showed stronger contribution of ARMS2 in AMD with RPD group versus AMD without RPD group, in comparison with CFH genotypes.
|
28593728 |
2018 |
|
rs1061170
|
|
|
0.040 |
GeneticVariation |
BEFREE |
CFH Y402H, ARMS2, HTRA1, and C3 were significantly associated with reticular pseudodrusen.
|
29801032 |
2018 |
|
rs1061170
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The ARMS2 single nucleotide polymorphism (SNP) rs10490924, HTRA1 SNPs rs11200638 and rs3793917, and CFH SNPs rs393955, rs1061170, and rs2274700 were associated with increased prevalence of RPD (all P < 0.05).
|
26681391 |
2016 |
|
rs10490924
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Logistic regression analysis revealed that age (odds ratio [OR]:1.10; 95% confidence interval [CI]: 1.04-1.18; p = 0.002), female gender (OR:4.26; 95%CI: 1.72-10.4; p = 0.002), T-allele at ARMS2 A69S (OR: 3.23; 95%CI: 1.36-7.68; p = 0.008) and RAP (OR: 4.25; 95%CI:1.49-12.1; p = 0.007) were risk factors for RPD.
|
24595987 |
2014 |
|
rs10490924
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The frequency of the T allele in ARMS2 A69S in patients with and without reticular pseudodrusen was 78.6% and 59.9%, respectively (P=.007).
|
23111182 |
2013 |
|
rs800292
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To pool the results of published data regarding association of ARMS2/LOC387715 A69S, CFH Y402H and CFH I62V genotypes with age-related macular degeneration (AMD) with and without reticular pseudodrusen (RPD).
|
28593728 |
2018 |
|
rs800292
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The frequency of risk variants of ARMS2 A69S was significantly higher in eyes with RPD than in those without RPD (85.7% vs 63.8%, P = 0.0009), although the frequency of CFH I62V was not significantly different between those with and without RPD.
|
24595987 |
2014 |
|
rs114254831
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six single nucleotide polymorphisms-rs10490924 (ARMS2), rs1061170 (CFH), rs2230199 (C3), rs116503776 and rs114254831 (C2/CFB), and rs943080 (VEGF-A)-and the genetic risk score (GRS) were assessed for association with RPD.
|
31558345 |
2019 |
|
rs116503776
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six single nucleotide polymorphisms-rs10490924 (ARMS2), rs1061170 (CFH), rs2230199 (C3), rs116503776 and rs114254831 (C2/CFB), and rs943080 (VEGF-A)-and the genetic risk score (GRS) were assessed for association with RPD.
|
31558345 |
2019 |
|
rs2230199
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six single nucleotide polymorphisms-rs10490924 (ARMS2), rs1061170 (CFH), rs2230199 (C3), rs116503776 and rs114254831 (C2/CFB), and rs943080 (VEGF-A)-and the genetic risk score (GRS) were assessed for association with RPD.
|
31558345 |
2019 |
|
rs943080
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six single nucleotide polymorphisms-rs10490924 (ARMS2), rs1061170 (CFH), rs2230199 (C3), rs116503776 and rs114254831 (C2/CFB), and rs943080 (VEGF-A)-and the genetic risk score (GRS) were assessed for association with RPD.
|
31558345 |
2019 |
|
rs11200638
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ARMS2 single nucleotide polymorphism (SNP) rs10490924, HTRA1 SNPs rs11200638 and rs3793917, and CFH SNPs rs393955, rs1061170, and rs2274700 were associated with increased prevalence of RPD (all P < 0.05).
|
26681391 |
2016 |
|
rs2274700
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ARMS2 single nucleotide polymorphism (SNP) rs10490924, HTRA1 SNPs rs11200638 and rs3793917, and CFH SNPs rs393955, rs1061170, and rs2274700 were associated with increased prevalence of RPD (all P < 0.05).
|
26681391 |
2016 |
|
rs393955
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ARMS2 single nucleotide polymorphism (SNP) rs10490924, HTRA1 SNPs rs11200638 and rs3793917, and CFH SNPs rs393955, rs1061170, and rs2274700 were associated with increased prevalence of RPD (all P < 0.05).
|
26681391 |
2016 |