Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs34301344
rs34301344
ARL11
0.010 GeneticVariation BEFREE Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data. 18337727

2008
dbSNP: rs755100942
rs755100942
ARL11
0.010 GeneticVariation BEFREE Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data. 18337727

2008
dbSNP: rs9282861
rs9282861
SULT1A1
0.010 GeneticVariation BEFREE The present study was conducted to confirm the association of a G638A polymorphism, Arg213His, in SULT1A1 with familial prostate cancer risk in a Japanese population. 18368507

2008
dbSNP: rs1114167843
rs1114167843
MSH2
0.010 GeneticVariation BEFREE Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M. 16963262

2006
dbSNP: rs1799977
rs1799977
MLH1
0.010 GeneticVariation BEFREE Carrier frequencies of the I219V mutation were compared between hereditary prostate cancer (HPC) patients, unselected PRCA cases, patients with benign prostate hyperplasia and controls, but no differences between the sample groups were found. 16963262

2006
dbSNP: rs35831931
rs35831931
MLH1
0.010 GeneticVariation BEFREE Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M. 16963262

2006
dbSNP: rs536562413
rs536562413
MSH6 ; FBXO11
0.010 GeneticVariation BEFREE Carrier frequencies of the I219V mutation were compared between hereditary prostate cancer (HPC) patients, unselected PRCA cases, patients with benign prostate hyperplasia and controls, but no differences between the sample groups were found. 16963262

2006
dbSNP: rs63750109
rs63750109
MLH1
0.010 GeneticVariation BEFREE Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M. 16963262

2006
dbSNP: rs17879961
rs17879961
CHEK2
0.010 GeneticVariation BEFREE I157T was identified in 16% of men with familial prostate cancer (OR = 3.8; P = 0.00002). 15087378

2004
dbSNP: rs137852593
rs137852593
AR
0.010 GeneticVariation BEFREE The AR R726L allele does not account for a significant proportion of early-onset and/or familial prostate cancer in the United States. 12539229

2003
dbSNP: rs78105154
rs78105154
ELAC2
0.010 GeneticVariation BEFREE An epidemiological study was done in sporadic PCa (n=98) and BPH (n=143) using 1 novel (Ser627Leu) and 2 previously described polymorphisms of the HPC2/ELAC2 gene. 12949798

2003
dbSNP: rs5030739
rs5030739
ELAC2
0.010 GeneticVariation BEFREE A truncating mutation was found in one hereditary prostate cancer (HPC) family, whereas two missense variants, Ser217Leu and Ala541Thr, were reported to be associated with increased PRCA risk in the general population. 11507049

2001