rs17879961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
I157T was identified in 16% of men with familial prostate cancer (OR = 3.8; P = 0.00002).
|
15087378 |
2004 |
rs1799977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carrier frequencies of the I219V mutation were compared between hereditary prostate cancer (HPC) patients, unselected PRCA cases, patients with benign prostate hyperplasia and controls, but no differences between the sample groups were found.
|
16963262 |
2006 |
rs2645429
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele of rs2645429 was significantly associated with prostate cancer risk in a Japanese familial prostate cancer population.
|
22546838 |
2012 |
rs34301344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data.
|
18337727 |
2008 |
rs35831931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M.
|
16963262 |
2006 |
rs4242382
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Assessing interactions of two loci (rs4242382 and rs10486567) in familial prostate cancer: statistical evaluation of epistasis.
|
24586834 |
2014 |
rs5030739
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A truncating mutation was found in one hereditary prostate cancer (HPC) family, whereas two missense variants, Ser217Leu and Ala541Thr, were reported to be associated with increased PRCA risk in the general population.
|
11507049 |
2001 |
rs536562413
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carrier frequencies of the I219V mutation were compared between hereditary prostate cancer (HPC) patients, unselected PRCA cases, patients with benign prostate hyperplasia and controls, but no differences between the sample groups were found.
|
16963262 |
2006 |
rs63750109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Second, the samples from Finnish hereditary prostate cancer (HPC) families were used for the screening of MLH1 mutations which produced twelve MLH1 sequence variants including two missense mutations, I219V, as in the PRCA-colon cancer patient, and V647M.
|
16963262 |
2006 |
rs755100942
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that Trp149Stop is not a predisposition allele in breast, prostate, or colorectal cancer in the Finnish population, and, while the Gly65Val variant may increase familial prostate cancer risk and the Cys148Arg change may affect both breast and prostate cancer risk, the evidence is not strong in these data.
|
18337727 |
2008 |
rs78105154
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An epidemiological study was done in sporadic PCa (n=98) and BPH (n=143) using 1 novel (Ser627Leu) and 2 previously described polymorphisms of the HPC2/ELAC2 gene.
|
12949798 |
2003 |
rs9282861
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study was conducted to confirm the association of a G638A polymorphism, Arg213His, in SULT1A1 with familial prostate cancer risk in a Japanese population.
|
18368507 |
2008 |