rs1800562
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The H63D variant was observed in 35% and the C282Y variant as heterozygous in 5% of patients with MDS with IOL.
|
25841232 |
2015 |
rs1800562
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Increased prevalence of HFE gene mutations is not a generalized feature of MDS, but some subgroups of MDS, especially those characterized by excessive accumulation of ringed sideroblasts, exhibit C282Y mutations at a higher frequency than in other forms of MDS and healthy controls.
|
17654685 |
2007 |
rs1800562
|
|
|
0.050 |
GeneticVariation |
BEFREE |
49 patients with MM were compared to 61 patients with myelodysplastic syndrome (MDS) concerning the incidence of two genetic variants of the HFE gene (C282Y and H63D) identified with PCR-RFLP.
|
17001480 |
2006 |
rs1800562
|
|
|
0.050 |
GeneticVariation |
BEFREE |
With C282Y, increased OR occurred in non-Hodgkin lymphoma, myeloproliferative disorders, and adenocarcinoma of prostate (2.0, 2.8, and 3.4, respectively); OR was decreased in myelodysplasia (0.4).
|
15018631 |
2004 |
rs1800562
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Genotypic testing of nonselected patients with the myelodysplastic syndrome (MDS) for the C282Y and H63D mutations of the HFE gene responsible for hereditary hemochromatosis revealed a significantly increased frequency of these mutations when compared to healthy blood donors reflecting the average population.
|
12624489 |
2003 |
rs1799945
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The H63D variant was observed in 35% and the C282Y variant as heterozygous in 5% of patients with MDS with IOL.
|
25841232 |
2015 |
rs1799945
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The results suggest that H63D mutations may not have clinical significance in Chinese patients with MDS and AA.
|
20563578 |
2010 |
rs1799945
|
|
|
0.040 |
GeneticVariation |
BEFREE |
49 patients with MM were compared to 61 patients with myelodysplastic syndrome (MDS) concerning the incidence of two genetic variants of the HFE gene (C282Y and H63D) identified with PCR-RFLP.
|
17001480 |
2006 |
rs1799945
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Genotypic testing of nonselected patients with the myelodysplastic syndrome (MDS) for the C282Y and H63D mutations of the HFE gene responsible for hereditary hemochromatosis revealed a significantly increased frequency of these mutations when compared to healthy blood donors reflecting the average population.
|
12624489 |
2003 |