Gene: GRN ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5848
rs5848
GRN ; FAM171A2
0.030 GeneticVariation BEFREE A single nucleotide polymorphism GRN rs5848 (3'UTR+78 C>T) was reported to alter the risk for frontotemporal lobar degeneration. 23342160

2013
dbSNP: rs5848
rs5848
GRN ; FAM171A2
0.030 GeneticVariation BEFREE No association of PGRN 3'UTR rs5848 in frontotemporal lobar degeneration. 19446372

2011
dbSNP: rs5848
rs5848
GRN ; FAM171A2
0.030 GeneticVariation BEFREE Variation at GRN 3'-UTR rs5848 is not associated with a risk of frontotemporal lobar degeneration in Dutch population. 19847305

2009
dbSNP: rs763841075
rs763841075
GRN
0.020 GeneticVariation BEFREE Alzheimer neuropathology without frontotemporal lobar degeneration hallmarks (TAR DNA-binding protein 43 inclusions) in missense progranulin mutation Cys139Arg. 27997711

2018
dbSNP: rs763841075
rs763841075
GRN
0.020 GeneticVariation BEFREE Association of the variant Cys139Arg at GRN gene to the clinical spectrum of frontotemporal lobar degeneration. 24503614

2014
dbSNP: rs63751180
rs63751180
GRN
0.010 GeneticVariation BEFREE Induced pluripotent stem cells (iPSCs) were generated from peripheral blood-derived erythroid progenitor cells obtained from a presymptomatic female carrying the heterozygous R418X progranulin (GRN) nonsense mutation, known to cause autosomal dominant frontotemporal lobar degeneration. 31707213

2019