Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs2943634 0.763 0.200 2 226203364 intergenic variant A/C;G snv 15
rs2228145
IL6R
0.602 0.720 1 154454494 missense variant A/C;T snv 0.38; 1.2E-05 57
rs1051931
PLA2G7
0.708 0.400 6 46705206 missense variant A/G snv 0.81 0.79 19
rs10757278
CDKN2B-AS1
0.620 0.520 9 22124478 intron variant A/G snv 0.40 44
rs1137101
LEPR
0.554 0.760 1 65592830 missense variant A/G snv 0.51 0.50 77
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs268
LPL
0.637 0.480 8 19956018 missense variant A/G snv 1.3E-02 1.3E-02 41
rs4994
ADRB3
0.578 0.640 8 37966280 missense variant A/G snv 0.11 9.2E-02 65
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58 134
rs2295490
TRIB3
0.724 0.320 20 388261 missense variant A/G;T snv 0.18; 4.0E-06 16
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06 223
rs4925
GSTO1
0.677 0.560 10 104263031 missense variant C/A snv 0.25 0.23 28
rs76863441
PLA2G7
0.672 0.440 6 46709361 missense variant C/A snv 4.5E-03 1.3E-03 25
rs2075291
APOA5 ; ZPR1
0.752 0.400 11 116790676 missense variant C/A;T snv 6.4E-03; 4.0E-06 15
rs1800206
PPARA
0.641 0.640 22 46218377 missense variant C/G snv 4.3E-02 4.2E-02 35
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02 131
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv 121
rs2910164
MIR3142HG ; MIR146A
0.447 0.880 5 160485411 mature miRNA variant C/G snv 0.71; 4.1E-06 0.70 193
rs1799945
LOC108783645 ; HFE
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10 226
rs1862513
RETN
0.763 0.360 19 7668907 upstream gene variant C/G;T snv 11
rs7903146
TCF7L2
0.554 0.680 10 112998590 intron variant C/G;T snv 93
rs1205
CRP
0.602 0.680 1 159712443 3 prime UTR variant C/T snv 0.30 46
rs17611
C5
0.732 0.480 9 121006922 missense variant C/T snv 0.47 0.36 14
rs2229616
MC4R
0.732 0.200 18 60372043 missense variant C/T snv 1.6E-02 1.6E-02 22
rs5443
CDCA3 ; GNB3
0.532 0.760 12 6845711 synonymous variant C/T snv 0.36 0.44 106