F2, coagulation factor II, thrombin, 2147

N. diseases: 490; N. variants: 42
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C4280698
Disease: Reduced prothrombin antigen
Reduced prothrombin antigen 		phenotype Finding 2 0.100 None 0
CUI: C4022610
Disease: Excessive bleeding from superficial cuts
Excessive bleeding from superficial cuts 		phenotype Pathologic Function 2 0.100 None 0
CUI: C0013491
Disease: Ecchymosis
Ecchymosis 		phenotype Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases Pathologic Function 41 2 0.100 None 0
CUI: C1837352
Disease: Childhood onset
Childhood onset 		phenotype Finding 56 0.100 None 0
CUI: C0151872
Disease: Prothrombin time increased
Prothrombin time increased 		phenotype Hemic and Lymphatic Diseases Finding 30 0.100 None 0
CUI: C4022608
Disease: Oral cavity bleeding
Oral cavity bleeding 		phenotype Pathologic Function 18 0.100 None 0
CUI: C4016343
Disease: DYSPROTHROMBINEMIA PROTHROMBIN HIMI-II
DYSPROTHROMBINEMIA PROTHROMBIN HIMI-II 		phenotype Finding 1 1 0.100 None 0 1
CUI: C3890031
Disease: prothrombin type 3 phenotype
prothrombin type 3 phenotype 		phenotype Finding 1 1 0.100 None 0 1
CUI: C1969572
Disease: Prolonged bleeding after dental extraction
Prolonged bleeding after dental extraction 		phenotype Pathologic Function 8 0.100 None 0
CUI: C0423798
Disease: Increased tendency to bruise
Increased tendency to bruise 		phenotype Wounds and Injuries Finding 133 14 0.100 None 0
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders 		group Hemic and Lymphatic Diseases Disease or Syndrome 267 31 0.400 None 0.960 50 2 1975 2020
CUI: C0553681
Disease: Hypofibrinogenemia
Hypofibrinogenemia 		disease Disease or Syndrome 60 14 0.040 None 1.000 4 1977 2017
CUI: C0151747
Disease: Renal tubular disorder
Renal tubular disorder 		disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Disease or Syndrome 64 5 0.010 None 1.000 1 1977 1977
CUI: C0272317
Disease: Hereditary factor II deficiency disease
Hereditary factor II deficiency disease 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases Disease or Syndrome 2 14 0.500 None 1.000 11 13 1978 2014
CUI: C0008533
Disease: Hemophilia B
Hemophilia B 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases Disease or Syndrome 59 125 0.080 None 0.875 8 1980 2018
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		disease Disease or Syndrome 1075 276 0.040 None 1.000 4 1980 2016
CUI: C0020640
Disease: Inherited Factor II deficiency
Inherited Factor II deficiency 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases Disease or Syndrome 2 13 0.800 strong 0.964 28 11 1983 2019
CUI: C3203356
Disease: Factor II deficiency
Factor II deficiency 		disease Hemic and Lymphatic Diseases Disease or Syndrome 1 4 0.400 None 0.938 16 1 1983 2019
CUI: C4722227
Disease: Hypoprothrombinemias
Hypoprothrombinemias 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases Disease or Syndrome 1 5 0.600 strong 0.929 14 2 1983 2019
CUI: C0018926
Disease: Hematemesis
Hematemesis 		phenotype Pathological Conditions, Signs and Symptoms; Digestive System Diseases Sign or Symptom 14 1 0.020 None 1.000 2 1984 2018
CUI: C0014867
Disease: Esophageal Varices
Esophageal Varices 		disease Digestive System Diseases Disease or Syndrome 56 5 0.020 None 1.000 2 1984 2017
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		group Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Disease or Syndrome 1180 140 0.010 None 1.000 1 1984 1984
CUI: C3160733
Disease: THROMBOPHILIA DUE TO THROMBIN DEFECT
THROMBOPHILIA DUE TO THROMBIN DEFECT 		phenotype Finding 4 2 0.400 strong 1.000 14 2 1986 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		disease Digestive System Diseases; Neoplasms Neoplastic Process 5725 942 0.400 None 1.000 56 1987 2019
CUI: C0023895
Disease: Liver diseases
Liver diseases 		group Digestive System Diseases Disease or Syndrome 1019 100 0.070 None 1.000 7 1987 2018