NAT2, N-acetyltransferase 2, 10

N. diseases: 311; N. variants: 10
Disease: Squamous cell carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.050 GeneticVariation disease BEFREE In conclusion, NAT2 rs1799930 polymorphism is an important factor of lung squamous carcinoma resistance in Chinese smoking males. 25005845 2014
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.050 GeneticVariation disease BEFREE Accumulation of certain alleles or genotypes of the CYP1A1, NAT2, GSTM1 and XPD seems to be associated with either increased or decreased risk to develop laryngeal SCC. 15914211 2005
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.050 GeneticVariation disease LHGDN Genetic polymorphism of N-acetyltransferase 2 in the susceptibility to laryngeal squamous cell carcinoma. 16155914 2005
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.050 GeneticVariation disease BEFREE N-Acetyltransferase 2 polymorphisms, cigarette smoking and alcohol consumption, and oral squamous cell cancer risk. 11751430 2001
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.050 GeneticVariation disease BEFREE These results are supported by logistic regressions of patients allowing interactions between tumour type (or treatment) and PY (or age), and indicate that the GSTM1-null genotype could be an important susceptibility factor for SQ while the NAT2-slow genotype may have an impact on other types of lung cancer. 10607733 2000