NAT2, N-acetyltransferase 2, 10

N. diseases: 311; N. variants: 10
Disease: Esophageal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.050 GeneticVariation group BEFREE N-acetyltransferase 2 polymorphisms and risk of esophageal cancer in a Chinese population. 24586291 2014
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.050 Biomarker group BEFREE There is a significant association between NAT2 acetylator phenotype and esophageal cancer in both smokers (OR=1.681, 95% CI=1.179-2.395) and non-smokers (OR=1.614, 95% CI=1.173-2.222). 24595082 2013
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.050 GeneticVariation group BEFREE In a case-control study, NAT2 slow acetylator genotype was not significantly associated with risk of esophageal cancer (OR 1.3, 95%CI = 0.78-2.2, P = 0.28). 17661210 2007
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.050 GeneticVariation group LHGDN Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus. 12773763 2003
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.050 GeneticVariation group BEFREE Genetic polymorphism of N-acetyltransferase 2 in patients with esophageal cancer. 11774959 2001