|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
IFN-γ, IP-10, TNF, TGF-β, and ADA quantified in PF showed significantly higher concentrations in PlTB patients when compared to nTB.
|
31619524 |
2019 |
|
Pleural Tuberculosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Younger age and high pleural fluid ADA level are associated with very high probability of TP.
|
30711154 |
2019 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Adenosine deaminase (ADA), IRISA-TB (interferon gamma ultrasensitive rapid immunosuspension assay), Xpert MTB/RIF, and ULTRA performance outcomes were evaluated in pleural fluid samples from 149 patients with suspected pleural TB.
|
31270183 |
2019 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Conclusion:</b> The sequential detection of ADA screening and T-SPOT assay was found to be an accurate and rapid method for identifying TB pleurisy from pleural effusion, which would promote effective treatment.
|
31379209 |
2019 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, only in two cases with rising values, ADA finally exceeded the cutoff limit, which concerned a man with rheumatoid pleurisy and a man with tuberculous pleurisy.
|
29218743 |
2018 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
IFN-γ, IP-10, and ADA in PlTB effusions are significantly higher than in non-PlTB cases.
|
30148839 |
2018 |
|
Pleural Tuberculosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Age, sex, previous contact with a TB patient, presence of lymphadenopathy, and pleural adenosine deaminase (ADA) levels were found to be independently associated with PT.
|
29408477 |
2018 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Adenosine deaminase (ADA) is currently used as a diagnostic marker for tuberculous pleuritis.
|
29043661 |
2018 |
|
Pleural Tuberculosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The combination of 3 assays had the highest sensitivity at 97.9%, with an AUC value of 0.964.T-SPOT.TB in pleural fluid performed better than that in peripheral blood and the ADA activity test in pleural fluid for tuberculous pleurisy diagnosis.
|
29381918 |
2017 |
|
Pleural Tuberculosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Pleural biopsies are especially indicated in the following circumstances: a) inconclusive pleural fluid analysis and negative sputum study, if adenosine deaminase (ADA) levels are unavailable; b) suspected multi-resistant tuberculosis; c) a need for differentiating tuberculous pleurisy (if it progresses with neutrophilia) and complicated parapneumonic effusion; d) malignant pleural effusion coexisting with very high ADA levels; e) effusion coexisting with lung cancer and negative pleural cytology; f) suspected mesothelioma; and g) need for implementing re-treatment for patients with relapse after chemotherapy.
|
28410823 |
2017 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Many CPRs for PT are available.In addition to ADA alone, none of them contributes significantly to diagnosis of PT.
|
28727272 |
2017 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Compared to the 95% sensitivity of adenosine deaminase, the most sensitive test for pleural tuberculosis, the sensitivities of the three PCR-based tests were very low.
|
24803060 |
2014 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Evaluation of real-time polymerase chain reaction, interferon-gamma, adenosine deaminase, and immunoglobulin A for the efficient diagnosis of pleural tuberculosis.
|
21227729 |
2011 |
|
Pleural Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Pleural fluid ADA, IgA-ELISA and PCR sensitivities for the diagnosis of pleural tuberculosis.
|
17852820 |
2007 |
|
Pleural Tuberculosis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We have evaluated polymerase chain reaction (PCR) directed to the IS6110 sequence of Mycobacterium tuberculosis, the determination of adenosine deaminase (ADA) activity, and measurement of interferon (IFN)-gamma levels in pleural fluid in the diagnosis of pleural TB.
|
11083686 |
2000 |