HOTAIR, HOX transcript antisense RNA, 100124700

N. diseases: 234; N. variants: 9
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.060 AlteredExpression disease BEFREE Therefore, lncRNA PACER is down-regulated in OA and regulates chondrocyte apoptosis by down-regulating lncRNA HOTAIR. 31113870 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.060 AlteredExpression disease BEFREE Down-regulation of HOTAIR could reverse the effect of LiCl on progression of OA rats. 31564232 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.060 AlteredExpression disease BEFREE In the present study, we identified that HOTAIR level was upregulated in OA cartilage tissues. 29907764 2018
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.060 AlteredExpression disease BEFREE Although HOTAIR showed no significant effect on the stability of ADAMTS-5 mRNA in normal articular chondrocytes, HOTAIR overexpression and knockdown respectively increased and decreased the ADAMTS-5 mRNA stability in OA articular chondrocytes. 29441864 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.060 AlteredExpression disease BEFREE It was observed that the expression level of miR-17-5p was lower and the level of HOTAIR was higher in samples of non-traumatic ONFH compared with OA. 28207735 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.060 AlteredExpression disease BEFREE Furthermore, in interleukin-1β (IL-1β)-induced TMJ OA in vitro model (primary rabbit condylar chondrocytes), the expressions of matrix metalloproteinase (MMP)-1, MMP3, MMP9 and HOTAIR were all dramatically increased. 27063559 2016