Disease: Hepatitis C, Chronic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic 		0.040 GeneticVariation disease BEFREE A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms. 30723271 2019
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic 		0.040 Biomarker disease BEFREE In addition, MICA is associated with HCC in patients with chronic hepatitis C. We have now compared the impact of REG and SOR on MICA in HCC cells, as well as the immunotherapeutic implications thereof. 29055152 2018
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic 		0.040 GeneticVariation disease BEFREE Polymorphisms in MICA, but not in DEPDC5, HCP5 or PNPLA3, are associated with chronic hepatitis C-related hepatocellular carcinoma. 28928439 2017
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic 		0.040 GeneticVariation disease BEFREE Interestingly, these genetic variants also affect the activity of hepatitis, or disease progression in chronic hepatitis C. In addition, polymorphisms in apoptosis-related genes such as RNF7, TULP1, and MERTK are associated with fibrosis progression, and DEPDC5 and MICA variants are associated with HCV-related hepatocellular carcinoma. 26211651 2016