DNM1L, dynamin 1 like, 10059

N. diseases: 273; N. variants: 15
Disease: Male infertility ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021364
Disease: Male infertility
Male infertility 		0.010 Biomarker phenotype BEFREE Therefore, these results demonstrate that inhibition of p38 activity prevents CdCl<sub>2</sub>-induced apoptotic GC-2spd cell death by reducing depolarization of mitochondrial membrane potential and mitochondrial ROS levels via ERK phosphorylation in a signal pathway different from the CdCl<sub>2</sub>-induced ERK/Drp1/p38 axis and suggest a therapeutic strategy for CdCl<sub>2</sub>-induced male infertility. 31676320 2019