Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.050 Biomarker disease BEFREE It is known that lncRNA PTCSC3 inhibits thyroid cancer and glioma and STAT3 promotes cancer development. 31171714 2019
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.050 Biomarker disease BEFREE Long noncoding RNA (lncRNA) PTCSC3 (hereafter PTCSC3 is used to represent lncRNA PTCSC3) inhibits glioma and thyroid cancer, indicating its potential tumor suppression function in other types of cancers. 31026090 2019
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.050 Biomarker disease BEFREE LncRNA PTCSC3 is a tumor suppressor in thyroid cancer, and its role in drug resistance of anaplastic thyroid cancer (ATC) to chemotherapy drug doxorubicin was investigated in this study. 29561707 2018
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.050 Biomarker disease BEFREE Previous studies have shown that PTCSC3 (Thyroid Carcinoma Susceptibility Candidate 3), miR-574-5p and Wnt/β-catenin were involved in PTC, but the potential pathogenic mechanism among them was still unclear. 28513866 2017
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.050 GeneticVariation disease BEFREE Association of rs944289, which was previously known to confer risk for thyroid cancer, with FA, and the correlation between PTCSC3 and NRG1 expression demonstrates that predisposing genetic factors are partly common for benign and malignant thyroid tumors, and imply broader roles of the pathways they underlie in thyroid tumorigenesis, not limited to carcinogenesis. 25562676 2015