ADAM8, ADAM metallopeptidase domain 8, 101

N. diseases: 81; N. variants: 2
Disease: Systemic Scleroderma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.020 AlteredExpression disease BEFREE ADAM8 expression was increased on antigen-presenting cells and T lymphocytes of SSc patients. 29689251 2018
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.020 AlteredExpression disease BEFREE Stretching also reduced the expression of CCL2 and ADAM8 in the skin at week 4, which are two genes known to be upregulated in both murine sclGvHD and the inflammatory subset of human SSc. 28261202 2017