CDK4, cyclin dependent kinase 4, 1019

N. diseases: 433; N. variants: 8
Disease: High Grade Sarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1334008
Disease: High Grade Sarcoma
High Grade Sarcoma 		0.010 GeneticVariation disease BEFREE Our results suggest that the co-overexpression of MDM2 and CDK4, along with multiple genetic factors, increases the tendency for high-grade sarcoma with a DDLPS-like morphology in transformed human BMSCs by accelerating their growth and migration and blocking their adipogenic potential. 31160689 2019