Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751297
Disease: Leptomeningeal Neoplasms
Leptomeningeal Neoplasms
0.010 Biomarker disease BEFREE Importantly, we demonstrated robust antitumor efficacy following regional intraventricular delivery of HER2-CAR T cells for the treatment of multifocal brain metastases and leptomeningeal disease.<b>Conclusions:</b> Our study shows the importance of CAR design in defining an optimized CAR T cell, and highlights intraventricular delivery of HER2-CAR T cells for treating multifocal brain metastases.<i></i>. 29061641 2018