Stomach Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, the expression level of CDKN1A was negatively correlated with the expression of MNX1-AS1 in GC tissues.
|
31210302 |
2019 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
CASC15 involvement in the tumorigenesis of GC occurs when CASC15 interacts with EZH2 and WDR5 to modulate CDKN1A in nucleus.
|
29489064 |
2018 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Taken together, these findings imply that AGAP2-AS1 upregulated by SP1 plays an important role in GC development and progression by suppressing P21 and E-cadherin, which suggests that AGAP2-AS1 is a potential diagnostic marker and therapeutic target for GC patients.
|
28209205 |
2017 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
By recruiting HDAC1, MORC2 suppresses p21 Waf1/Cip1 in gastric cancer.
|
26098774 |
2015 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The purpose of this report was to identify a novel tri-allelic insertion/deletion (INDEL) polymorphism (rs4135235) involving a poly-T sequence in the promoter region of p21(Waf1/Cip1) gene and to explore its role in gastric cancer (GC).
|
24387689 |
2014 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
SNPs located in BAX and CDKN1A genes are closely associated with clinical outcomes in patients with gastric cancer.
|
25267570 |
2014 |
Stomach Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our results demonstrate that STAT3, but not STAT5, is involved in GC cell growth and cell cycle progression through regulation of gene expression, such as Bcl-2, p16(ink4a) and p21(waf1/cip1).
|
22328012 |
2012 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
PD98059 synergistically potentiates TSA-induced GC growth arrest and apoptosis by manipulating NF-κB and p21(WAF1/CIP1) independent of Notch.
|
22781708 |
2012 |
Stomach Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We previously showed that ATBF1 expression inversely correlated with the malignant character of gastric cancer and that ATBF1 enhanced the promoter activity of p21Waf1/Cip1.
|
20599712 |
2010 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results suggest that hypermethylation does not contribute to P21(CIP1) and P27(KIP1) silencing in gastric cancer, and that the role of these genes in the gastric tumorigenesis pathways should be studied further in the Pará state population.
|
20668328 |
2010 |
Stomach Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Histone H3 acetylation is associated with reduced p21(WAF1/CIP1) expression by gastric carcinoma.
|
15586362 |
2005 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Expression of p21(WAF1) and p53 and polymorphism of p21(WAF1) gene in gastric carcinoma.
|
15069711 |
2004 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
p21/waf1/cip1 in gastric cancer: associations with histopathological subtypes, lymphonodal metastasis, prognosis and p53 status.
|
11521990 |
2001 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
TGF-beta-induced cell-cycle arrest through the p21(WAF1/CIP1)-G1 cyclin/Cdks-p130 pathway in gastric-carcinoma cells.
|
10508488 |
1999 |