Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.310 GeneticVariation disease BEFREE Cocaine induced pathological A2AR-D2R-Sigma1R complexes may form a long-term memory with a strong and permanent D2R brake, leading to cocaine addiction. 30384981 2018
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.310 Biomarker disease CTD_human Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory. 16132061 2006
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.310 Biomarker disease CTD_human Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward. 12736327 2003