|
Ovarian Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
|
28598010 |
2017 |
|
Malignant neoplasm of ovary
|
0.010 |
Biomarker
|
disease |
BEFREE |
DLEU1 contributes to ovarian carcinoma tumourigenesis and development by interacting with miR-490-3p and altering CDK1 expression.
|
28598010 |
2017 |
|
Endometrial Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
DLEU1 was upregulated in EC tissues and cells.
|
30001771 |
2018 |
|
Malignant neoplasm of endometrium
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
DLEU1 was upregulated in EC tissues and cells.
|
30001771 |
2018 |
|
Tumor Cell Invasion
|
0.090 |
AlteredExpression
|
phenotype |
BEFREE |
DLEU1 overexpression promoted the proliferation, migration, and invasion, but inhibited the apoptosis of NSCLC cells by upregulating CDK1 expression, binding with SRC and altering the expression of P70(S6K), MMP2 and E-cadherin.
|
30551552 |
2019 |
|
Carcinogenesis
|
0.040 |
Biomarker
|
phenotype |
BEFREE |
DLEU1 promoted tumorigenesis and progression of NSCLC, and might be a promising therapeutic target for NSCLC.
|
30551552 |
2019 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
DLEU1 promoted tumorigenesis and progression of NSCLC, and might be a promising therapeutic target for NSCLC.
|
30551552 |
2019 |
|
Leukemia, T-Cell, Chronic
|
0.010 |
Biomarker
|
disease |
BEFREE |
A case of T-cell chronic lymphocytic leukemia (T-CLL) expressing a peculiar phenotype (E+, OKM1+, Leu 1+, OKT3- and IgG EA-).
|
6193857 |
1983 |
|
Blood urea nitrogen measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
|
31152163 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
|
31264924 |
2019 |
|
Maculopathy with diabetes mellitus
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity.
|
31264924 |
2019 |
|
Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.
|
19570815 |
2009 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Lipoprotein (a) measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure.
|
30108283 |
2018 |
|
Glioblastoma Multiforme
|
0.020 |
Biomarker
|
disease |
BEFREE |
Accordingly, our experimental data revealed that SP1-DLEU1-miR-4429 formed a feedback loop to promote GBM development, providing a new evidence for the role of DLEU1 in GBM.
|
31713587 |
2019 |
|
Chronic Lymphocytic Leukemia
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
All the deletions included the noncoding RNA locus DLEU1 (previously BCMS), which is considered to be the most likely CLL-associated candidate tumor suppressor gene within the 13q14 region.
|
19963108 |
2009 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
All the deletions included the noncoding RNA locus DLEU1 (previously BCMS), which is considered to be the most likely CLL-associated candidate tumor suppressor gene within the 13q14 region.
|
19963108 |
2009 |
|
Tumor Progression
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Although accumulating evidence has shown the important function of long non-coding RNAs (lncRNAs) in tumor progression and chemotherapy resistance, the role of lncRNA DLEU1 in regulating proliferation, invasion, and chemoresistance of bladder cancer (BCA) cells remains largely unknown.
|
30984249 |
2019 |
|
Multiple Sclerosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
|
24076602 |
2013 |
|
Secondary malignant neoplasm of lymph node
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
And highly expressed DLEU1 was relevant to tumor size, advanced stage of pathology and lymph node metastasis in GC patients.
|
29282356 |
2018 |
|
Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.
|
30575882 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Because of these results and that no mutations were detected on the two genes in a previous study, we think that Leu1 and Leu2 can be excluded as tumor suppressor genes.
|
10516767 |
1999 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Besides, xenograft tumors in nude mice demonstrated that DLEU1 overexpression accelerated tumor growth.
|
30551552 |
2019 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Characterizing rare and low-frequency height-associated variants in the Japanese population.
|
31562340 |
2019 |
|
Leukemia, Myelocytic, Acute
|
0.010 |
Biomarker
|
disease |
BEFREE |
Collectively, circRNA-DLEU2 accelerated human AML by suppressing miR-496 and promoting PRKACB expression.
|
30037980 |
2018 |