SEMA3A, semaphorin 3A, 10371

N. diseases: 202; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0268731
Disease: Renal glomerular disease
Renal glomerular disease
0.020 Biomarker group BEFREE We have shown that Sema3A regulates podocyte shape and that excess Sema3A signaling induces glomerular disease and aggravates diabetic nephropathy. 27787866 2017
CUI: C0268731
Disease: Renal glomerular disease
Renal glomerular disease
0.020 Biomarker group BEFREE We recently discovered that after completion of kidney development, Sema3a gain-of-function in podocytes leads to proteinuric glomerular disease in mice. 24464477 2014