NDRG1, N-myc downstream regulated 1, 10397

N. diseases: 225; N. variants: 4
Disease: Anoxia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003130
Disease: Anoxia
Anoxia 		0.040 AlteredExpression phenotype LHGDN These results showed for the first time that Egr-1 regulates NDRG1 transcription through an overlapping Egr-1/Sp1 binding site that acts as a major site of positive regulation of the NDRG1 promoter by hypoxia signaling. 17909017 2007
CUI: C0003130
Disease: Anoxia
Anoxia 		0.040 AlteredExpression phenotype LHGDN Identification of mRNAs that continue to associate with polysomes during hypoxia. 17488873 2007
CUI: C0003130
Disease: Anoxia
Anoxia 		0.040 AlteredExpression phenotype LHGDN Comparative proteomic analysis of hypoxia-treated and untreated human leukemic U937 cells. 16622835 2006
CUI: C0003130
Disease: Anoxia
Anoxia 		0.040 AlteredExpression phenotype LHGDN We hypothesize that the mechanism of Cap43 overexpression in cancer cells involves a state of hypoxia characteristic of cancer cells where the Cap43 protein becomes a signature for this hypoxic state. 12429530 2002