FST, follistatin, 10468

N. diseases: 182; N. variants: 7
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.030 AlteredExpression disease BEFREE Plasma proinflammatory cytokines and myokine follistatin were similarly elevated in vehicle-treated young and mature adult mice at 18 h after sepsis. 29979626 2018
CUI: C0243026
Disease: Sepsis
Sepsis 		0.030 Biomarker disease BEFREE Studies on transgenic mice and those with gene knockouts, together with blocking studies using exogenous follistatin, have established that activin A plays critical roles in the onset of cachexia, acute and chronic inflammatory responses such as septicemia, colitis and asthma, and fibrosis. 21353885 2011
CUI: C0243026
Disease: Sepsis
Sepsis 		0.030 Biomarker disease LHGDN Circulatory concentrations of activin and FS are elevated in patients diagnosed with septicemia, consistent with potential roles in the systemic inflammatory response. 12720540 2003