Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
CAP2 expression was significantly associated with tumor size, poor differentiation, portal vein invasion, and intrahepatic metastasis.
|
23022774 |
2013 |
Bipolar Disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A linkage and exome study implicates rare variants of KANK4 and CAP2 in bipolar disorder in a multiplex family.
|
31400178 |
2020 |
Borderline Personality Disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our studysuggests involvement of KANK4 or CAP2 or both in BPD in this family.
|
31400178 |
2020 |
Bronchopulmonary Dysplasia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our studysuggests involvement of KANK4 or CAP2 or both in BPD in this family.
|
31400178 |
2020 |
Supraventricular tachycardia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
CAP2 mutation leads to impaired actin dynamics and associates with supraventricular tachycardia and dilated cardiomyopathy.
|
30518548 |
2019 |
Atrial Fibrillation
|
0.010 |
Biomarker
|
disease |
BEFREE |
We studied the device arms of 4 prospective Food and Drug Administration trials: PROTECT-AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) (n=463); PREVAIL (Evaluation of the Watchman LAA Closure Device in Patients With Atrial Fibrillation Versus Long Term Warfarin Therapy) (n=269); CAP (Continued Access to PROTECT AF registry) (n=566); and CAP2 (Continued Access to PREVAIL registry) (n=578).
|
29752398 |
2018 |
Malignant neoplasm of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cyclase-associated protein 2 (CAP2) protein is reported to be upregulated in hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.
|
30047046 |
2018 |
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
CAP2 may serve as a prognostic indicator for patients with gastic cancer.
|
30047046 |
2018 |
Malignant neoplasm of stomach
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, its expression in gastric cancer remains unknown, this study was to investigate CAP2 expression and its prognostic significance in gastric cancer.
|
30047046 |
2018 |
melanoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cyclase-associated protein 2 (CAP2) protein is reported to be upregulated in hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.
|
30047046 |
2018 |
Breast Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Cyclase-associated protein 2 (CAP2) protein is reported to be upregulated in hepatocellular carcinoma (HCC), human breast cancer, and malignant melanoma.
|
30047046 |
2018 |
Stomach Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, its expression in gastric cancer remains unknown, this study was to investigate CAP2 expression and its prognostic significance in gastric cancer.
|
30047046 |
2018 |
Tumor Cell Invasion
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Statistical analysis shows that the expression of CAP2 was correlated with tumor size, Lauren's classification, depth of invasion, lymph node and distant metastases, and regional lymph node stage, TNM stage, but not with age, sex, histology classification, and histologic differentiation.
|
30047046 |
2018 |
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
CAP2 may serve as a prognostic indicator for patients with gastic cancer.
|
30047046 |
2018 |
Secondary Neoplasm
|
0.010 |
AlteredExpression
|
group |
BEFREE |
For the first time, we found that CAP2 was upregulated in gastic cancer, and was associated with lymph node and distant metastases.
|
30047046 |
2018 |
Conduction disorder of the heart
|
0.010 |
Biomarker
|
group |
BEFREE |
Finally, of the 42 suggestively associated loci, AJAP1 was suggestively associated with QT in a prior East Asian GWAS; in contrast BVES and CAP2 murine knockouts caused cardiac conduction defects.
|
29213071 |
2017 |