|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
|
29844566 |
2018 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
|
29326435 |
2019 |
|
Multiple Sclerosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.
|
24076602 |
2013 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Genetically, a subset of the congenital cases display NCOA2 gene rearrangements, whereas tumors occurring in older children or adults harbor MYOD1 gene mutations with or without coexisting PIK3CA mutations.
|
26501226 |
2016 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Recently, two fusion genes were described in mesenchymal chondrosarcomas: a recurrent HEY1-NCOA2 found in tumors that had not been cytogenetically characterized and an IRF2BP2-CDX1 found in a tumor carrying a t(1;5)(q42;q32) translocation as the sole chromosomal abnormality.
|
24839999 |
2014 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
This study reports the morphologic spectrum of UTROSCT and confirms the recently reported recurrent NCOA2-3 gene fusions, in addition to identifying novel rearrangements involving NCOA1 in these tumors.
|
31464709 |
2020 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
A solitary fibrous tumor-mimicking tumor with the AHRR-NCOA2 gene has been isolated as angiofibroma of soft tissue.
|
28759137 |
2017 |
|
Alkaline phosphatase measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
|
30275531 |
2018 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
QT interval feature (observable entity)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
|
24952745 |
2014 |
|
Mesenchymal Chondrosarcoma
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
The morphologic features are distinct from other sarcomas associated with NCOA2 gene fusions, including mesenchymal chondrosarcoma, congenital/infantile spindle cell rhabdomyosarcoma, and soft tissue angiofibroma.
|
30179902 |
2018 |
|
Mesenchymal Chondrosarcoma
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Pancreatic involvement by mesenchymal chondrosarcoma harboring the HEY1-NCOA2 gene fusion.
|
27544802 |
2016 |
|
Mesenchymal Chondrosarcoma
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Our findings show 2 variants of the HEY1-NCOA2 gene fusion: HEY1 (exon 4)-NCOA2 (exon 13) and HEY1 (exon 4)-NCOA2 (exon 14), in both mesenchymal chondrosarcoma patients.
|
30819134 |
2019 |
|
Childhood Mesenchymal Chondrosarcoma
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
The transcription factor gene NCOA2 was one of the candidates identified in a mesenchymal chondrosarcoma.
|
22034177 |
2012 |
|
Childhood Mesenchymal Chondrosarcoma
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
Pancreatic involvement by mesenchymal chondrosarcoma harboring the HEY1-NCOA2 gene fusion.
|
27544802 |
2016 |
|
Childhood Mesenchymal Chondrosarcoma
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
Our findings show 2 variants of the HEY1-NCOA2 gene fusion: HEY1 (exon 4)-NCOA2 (exon 13) and HEY1 (exon 4)-NCOA2 (exon 14), in both mesenchymal chondrosarcoma patients.
|
30819134 |
2019 |
|
Childhood Mesenchymal Chondrosarcoma
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
The morphologic features are distinct from other sarcomas associated with NCOA2 gene fusions, including mesenchymal chondrosarcoma, congenital/infantile spindle cell rhabdomyosarcoma, and soft tissue angiofibroma.
|
30179902 |
2018 |
|
Angiofibroma
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Angiofibroma of soft tissue with fibrohistiocytic features and intratumor genetic heterogeneity of NCOA2 gene rearrangement revealed by chromogenic in situ hybridization: a case report.
|
24888778 |
2014 |
|
Angiofibroma
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes.
|
22337624 |
2012 |
|
Juvenile angiofibroma
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes.
|
22337624 |
2012 |
|
Juvenile angiofibroma
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Angiofibroma of soft tissue with fibrohistiocytic features and intratumor genetic heterogeneity of NCOA2 gene rearrangement revealed by chromogenic in situ hybridization: a case report.
|
24888778 |
2014 |
|
leukemia
|
0.060 |
GeneticVariation
|
disease |
LHGDN |
The ETV6-NCOA2 fusion may define a novel subgroup of acute leukemia with T-lymphoid and myeloid features, which is associated with a high prevalence of NOTCH1 mutations.
|
18281529 |
2008 |
|
leukemia
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
This similarity is also apparent at the molecular genetic level, in-as-much as the MOZ gene in 8p11 is rearranged in both the translocation and the inversion; in t(8;16)-positive leukemia, a MOZ-CBP chimeric gene is generated, whereas inv(8) has been shown to generate a MOZ-TIF2 fusion gene.
|
11342350 |
2000 |
|
Childhood Leukemia
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
This similarity is also apparent at the molecular genetic level, in-as-much as the MOZ gene in 8p11 is rearranged in both the translocation and the inversion; in t(8;16)-positive leukemia, a MOZ-CBP chimeric gene is generated, whereas inv(8) has been shown to generate a MOZ-TIF2 fusion gene.
|
11342350 |
2000 |