ATG7, autophagy related 7, 10533

N. diseases: 179; N. variants: 17
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.010 Biomarker disease BEFREE Loss of Atg7 resulted in increased production of IL-1β and pyroptosis, consistent with enhanced inflammasome activation.Furthermore, we demonstrated that <i>P. aeruginosa</i> flagellin is a chief trigger of inflammasome activation in the sepsis model. 28258192 2017