UPK3B, uroplakin 3B, 105375355

N. diseases: 82; N. variants: 3
Disease: Retinopathy of Prematurity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.020 Biomarker disease BEFREE The developmental cell death was slightly accelerated in ROP rats; however, no visible changes in the morphology of retinal layers were observed on P35. 31788758 2020
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.020 Biomarker disease BEFREE Vasodilation of retinal arterioles induced by acetylcholine, an endothelium-dependent vasodilator, was smaller in P35 ROP rats than age-matched controls, whereas retinal vasodilator responses to the nitric oxide (NO) donor NOR3 were unaltered.<b>Conclusions</b>: Phenotypic changes in pericytes occur in the ROP model rats and endothelium-dependent vasodilatory mechanisms in retinal blood vessels are impaired. 31317786 2019