PROCR, protein C receptor, 10544

N. diseases: 110; N. variants: 20
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.120 Biomarker disease BEFREE Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C system (THBD and PROCR) may similarly be associated with early-onset ischemic stroke. 30383853 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.120 GeneticVariation disease GWASCAT Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis. 26908601 2016
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.120 Biomarker disease BEFREE The cytoprotective effects are protease activated receptor 1 (PAR-1) and endothelial protein C receptor (EPCR) dependent and likely underlie protective effects of APC in animal models of sepsis, myocardial infarction and ischemic stroke. 25032959 2014