Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.070 PosttranslationalModification group BEFREE Human anterior gradient proteins AGR2 and AGR3 are overexpressed in a variety of adenocarcinomas and are often secreted in cancer patients' specimens, which suggests a role for AGR proteins in intra and extracellular compartments. 31611954 2019
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.070 Biomarker group BEFREE The cancer-associated protein Anterior Gradient 2 (AGR2) has been described, predominantly in adenocarcinomas. 29937991 2018
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.070 AlteredExpression group BEFREE Anterior gradient-2 (AGR2) is overexpressed in diverse human adenocarcinomas and it exists in both intracellular and extracellular spaces. 28481872 2017
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.070 Biomarker group BEFREE Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer. 22605983 2012
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.070 AlteredExpression group BEFREE Induced AREG expression in adenocarcinoma cells is able to rescue the transformed phenotype that is lost when AGR2 expression is reduced. 21454516 2011
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.070 AlteredExpression group BEFREE Interestingly, within adenocarcinoma samples, there was a slight trend toward lower levels of AGR2 with increasing Gleason score. 21144054 2010
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.070 Biomarker group BEFREE Although a prognostic value of AGR2 seems unlikely, further studies are warranted to investigate the biological role of AGR2 in pancreatic adenocarcinomas. 19609859 2009