Spinal Muscular Atrophy
|
0.030 |
Biomarker
|
disease |
BEFREE |
Deletion of NAIP and p44 is observed more often in severe SMA, but there is no evidence that these genes play a role in the pathology of the disease.
|
9245983 |
1997 |
Spinal Muscular Atrophy
|
0.030 |
Biomarker
|
disease |
BEFREE |
Here, we show that the gene encoding p44, a subunit of the basal transcription factor TFIIH, is duplicated in the SMA region and that the p44 gene products (p44t and p44c) differ by three amino acid changes.
|
8981949 |
1997 |
Human anaplasmosis due to Anaplasma phagocytophilum
|
0.050 |
Biomarker
|
disease |
BEFREE |
Southern blot results revealed the existence of multigenes homologous to the P44 gene in the genome of the HGE agent.
|
9620397 |
1998 |
Human anaplasmosis due to Anaplasma phagocytophilum
|
0.050 |
Biomarker
|
disease |
BEFREE |
, p44 from the agent of human granulocytic ehrlichiosis, msp-2 and msp-4 from Anaplasma marginale, and map-1 from Cowdria ruminantium.
|
9705412 |
1998 |
Human anaplasmosis due to Anaplasma phagocytophilum
|
0.050 |
Biomarker
|
disease |
BEFREE |
Characterization of p44-homologous genes expressed by the HGE agent in a tissue culture would assist in understanding a role of the p44 multigene family in pathogenesis and immune response in HGE.
|
10364227 |
1999 |
Spinal Muscular Atrophy
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Here we present the molecular analysis of SMA candidate genes, the survival motor neuron gene (SMN), the neuronal apoptosis inhibitory protein gene (NAIP) and the p44 gene.
|
10206524 |
1999 |
Human anaplasmosis due to Anaplasma phagocytophilum
|
0.050 |
Biomarker
|
disease |
BEFREE |
Expression of interleukin-1beta, tumor necrosis factor alpha, and interleukin-6 in human peripheral blood leukocytes exposed to human granulocytic ehrlichiosis agent or recombinant major surface protein P44.
|
10816490 |
2000 |
Human anaplasmosis due to Anaplasma phagocytophilum
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Similarly, the p44 genes were differentially expressed in infected C3H mice, in SCID mice, and in cultured HGE bacteria.
|
12183586 |
2002 |
Malignant neoplasm of prostate
|
0.050 |
Biomarker
|
disease |
BEFREE |
The forced nuclear localization of p44 inhibited prostate cancer cell growth by G1 cell-cycle arrest.
|
17032745 |
2006 |
Prostate carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
The forced nuclear localization of p44 inhibited prostate cancer cell growth by G1 cell-cycle arrest.
|
17032745 |
2006 |
Hepatitis C
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Moreover, the induction of expression at day 28, and pretreatment levels of OAS1 and IFI44 correlated with hepatitis C virus RNA reduction at day 28 (P < 0.05).
|
17302252 |
2006 |
Benign Prostatic Hyperplasia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Consistently, mice lacking one allele of the p44 gene developed prostatic hyperplasia.
|
17032745 |
2006 |
Prostatic Hyperplasia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Consistently, mice lacking one allele of the p44 gene developed prostatic hyperplasia.
|
17032745 |
2006 |
Hepatitis C
|
0.030 |
Biomarker
|
disease |
BEFREE |
The interferon-alpha (IFN-alpha)-inducible protein IFI44 is associated with hepatitis C virus (HCV) infection, and its function is unknown.
|
17784819 |
2007 |
Lupus Erythematosus, Systemic
|
0.020 |
Biomarker
|
disease |
BEFREE |
Real-time RT-PCR experiments confirmed the up-regulation of selected IFI genes (IFI27, IFI44, and IFI44L) in the SLE synovial tissue.
|
17469140 |
2007 |
Leydig Cell Tumor
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We studied the expression of p44 and protein arginine methyltransferase 5 in developing fetal testis and adult testicular tumors, including seminomas and Leydig cell tumors.
|
17437848 |
2007 |
Seminoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Compared to adult nonneoplastic testes, human seminoma and Leydig tumor cells showed a marked decrease in nuclear expression of p44 and protein arginine methyltransferase 5 with a concomitant marked increase in cytoplasmic expression of these proteins.
|
17437848 |
2007 |
Testicular Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
We studied the expression of p44 and protein arginine methyltransferase 5 in developing fetal testis and adult testicular tumors, including seminomas and Leydig cell tumors.
|
17437848 |
2007 |
Spontaneous abortion
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
Abortion, Tubal
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
Early Pregnancy Loss
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
Miscarriage
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
Malignant neoplasm of prostate
|
0.050 |
Biomarker
|
disease |
BEFREE |
Our results indicate that nuclear p44 and cytoplasmic p44 have distinct and opposing functions in the regulation of prostate cancer cell proliferation.
|
18356297 |
2008 |
Prostate carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Our results indicate that nuclear p44 and cytoplasmic p44 have distinct and opposing functions in the regulation of prostate cancer cell proliferation.
|
18356297 |
2008 |
androgen independent prostate cancer
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Importantly, we also demonstrate that altered p44 expression is associated with androgen-independent prostate cancer.
|
18356297 |
2008 |