IFI44, interferon induced protein 44, 10561

N. diseases: 38; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021400
Disease: Influenza
Influenza
0.300 Biomarker disease CTD_human A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2. 23326326 2013
CUI: C0000786
Disease: Spontaneous abortion
Spontaneous abortion
0.300 Biomarker phenotype CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C0000822
Disease: Abortion, Tubal
Abortion, Tubal
0.300 Biomarker phenotype CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C3830362
Disease: Early Pregnancy Loss
Early Pregnancy Loss
0.300 Biomarker phenotype CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C4552766
Disease: Miscarriage
Miscarriage
0.300 Biomarker disease CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.050 AlteredExpression disease BEFREE Expression of PRMT5 and p44 in lung and prostate cancer cells was silenced and their target genes were identified. 27480244 2016
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 AlteredExpression disease BEFREE Expression of PRMT5 and p44 in lung and prostate cancer cells was silenced and their target genes were identified. 27480244 2016
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.050 Biomarker disease BEFREE Cell proliferation assays with N- and C- terminal deletion mutations indicated that the central portion of p44 is required for nuclear p44 mediated prostate cancer growth inhibition. 23734213 2013
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 Biomarker disease BEFREE Cell proliferation assays with N- and C- terminal deletion mutations indicated that the central portion of p44 is required for nuclear p44 mediated prostate cancer growth inhibition. 23734213 2013
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.050 AlteredExpression disease BEFREE In contrast to findings in prostate cancer, the expression of p44 shows strong cytoplasmic expression in morphologically normal terminal ductal lobular units, while nuclear p44 is observed in both ductal carcinoma in situ and invasive carcinoma. 19840198 2010
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 AlteredExpression disease BEFREE In contrast to findings in prostate cancer, the expression of p44 shows strong cytoplasmic expression in morphologically normal terminal ductal lobular units, while nuclear p44 is observed in both ductal carcinoma in situ and invasive carcinoma. 19840198 2010
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.050 Biomarker disease BEFREE Our results indicate that nuclear p44 and cytoplasmic p44 have distinct and opposing functions in the regulation of prostate cancer cell proliferation. 18356297 2008
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 Biomarker disease BEFREE Our results indicate that nuclear p44 and cytoplasmic p44 have distinct and opposing functions in the regulation of prostate cancer cell proliferation. 18356297 2008
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.050 Biomarker disease BEFREE The forced nuclear localization of p44 inhibited prostate cancer cell growth by G1 cell-cycle arrest. 17032745 2006
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 Biomarker disease BEFREE The forced nuclear localization of p44 inhibited prostate cancer cell growth by G1 cell-cycle arrest. 17032745 2006
Human anaplasmosis due to Anaplasma phagocytophilum
0.050 AlteredExpression disease BEFREE Similarly, the p44 genes were differentially expressed in infected C3H mice, in SCID mice, and in cultured HGE bacteria. 12183586 2002
Human anaplasmosis due to Anaplasma phagocytophilum
0.050 Biomarker disease BEFREE Expression of interleukin-1beta, tumor necrosis factor alpha, and interleukin-6 in human peripheral blood leukocytes exposed to human granulocytic ehrlichiosis agent or recombinant major surface protein P44. 10816490 2000
Human anaplasmosis due to Anaplasma phagocytophilum
0.050 Biomarker disease BEFREE Characterization of p44-homologous genes expressed by the HGE agent in a tissue culture would assist in understanding a role of the p44 multigene family in pathogenesis and immune response in HGE. 10364227 1999
Human anaplasmosis due to Anaplasma phagocytophilum
0.050 Biomarker disease BEFREE Southern blot results revealed the existence of multigenes homologous to the P44 gene in the genome of the HGE agent. 9620397 1998
Human anaplasmosis due to Anaplasma phagocytophilum
0.050 Biomarker disease BEFREE , p44 from the agent of human granulocytic ehrlichiosis, msp-2 and msp-4 from Anaplasma marginale, and map-1 from Cowdria ruminantium. 9705412 1998
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.030 Biomarker disease BEFREE Expression of interferon-stimulated genes (ISGs) EI2AK2, ISG15, Mx1 and IFI44 was increased in pDCs from HIV-1-HCV-coinfected individuals and was correlated with fibrosis score (Fibroscan, www.echosens.com, Paris, France and aspartate-aminotransferase/platelet-ratio index score, P = 0.026 and 0.019, respectively). 28492391 2017
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.030 Biomarker disease BEFREE The interferon-alpha (IFN-alpha)-inducible protein IFI44 is associated with hepatitis C virus (HCV) infection, and its function is unknown. 17784819 2007
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.030 AlteredExpression disease BEFREE Moreover, the induction of expression at day 28, and pretreatment levels of OAS1 and IFI44 correlated with hepatitis C virus RNA reduction at day 28 (P < 0.05). 17302252 2006
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy
0.030 GeneticVariation disease BEFREE Here we present the molecular analysis of SMA candidate genes, the survival motor neuron gene (SMN), the neuronal apoptosis inhibitory protein gene (NAIP) and the p44 gene. 10206524 1999
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy
0.030 Biomarker disease BEFREE Deletion of NAIP and p44 is observed more often in severe SMA, but there is no evidence that these genes play a role in the pathology of the disease. 9245983 1997