SORBS1, sorbin and SH3 domain containing 1, 10580

N. diseases: 124; N. variants: 28
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE SORBS1 has been linked to obesity and insulin signaling. 24905834 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.030 GeneticVariation disease BEFREE An association study showed that a missense variant of the SORBS1 gene is protective against obesity and diabetes. 12849814 2003
CUI: C0028754
Disease: Obesity
Obesity 		0.030 GeneticVariation disease BEFREE In conclusion, our results suggest that the A228 allele of the T228A polymorphism of the SORBS1 gene is a protective factor for both obesity and diabetes, and also imply that the SORBS1 gene plays an important role in the pathogenesis of human disorders with insulin resistance. 11532984 2001