SH2B2, SH2B adaptor protein 2, 10603

N. diseases: 59; N. variants: 1
Disease: Antiphospholipid Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085278
Disease: Antiphospholipid Syndrome
Antiphospholipid Syndrome 		0.050 Biomarker disease BEFREE The comparison of real world and core laboratory antiphospholipid antibody ELISA results from antiphospholipid syndrome alliance for clinical trials & international networking (APS ACTION) clinical database and repository analysis. 30685523 2019
CUI: C0085278
Disease: Antiphospholipid Syndrome
Antiphospholipid Syndrome 		0.050 GeneticVariation disease BEFREE However, the use of DOACs in unusual VTE, including cerebral venous thrombosis (CVT) and splanchnic venous thrombosis (SVT), and in patients with biological thrombophilia including minor thrombophilia (Factor V Leiden and prothrombin G20210A), major innate thrombophilia (protein C and S deficiency, and antithrombin) and major acquired thrombophilia (antiphospholipid syndrome [APS]), remains controversial due to the paucity of available data. 29402471 2018
CUI: C0085278
Disease: Antiphospholipid Syndrome
Antiphospholipid Syndrome 		0.050 GeneticVariation disease BEFREE Development of clinical features of APS in monozygotic twins points to an underlying genetic basis in the pathogenesis of anti-phospholipid syndrome. 23154322 2013
CUI: C0085278
Disease: Antiphospholipid Syndrome
Antiphospholipid Syndrome 		0.050 GeneticVariation disease BEFREE Comparative incidence of a first thrombotic event in purely obstetric antiphospholipid syndrome with pregnancy loss: the NOH-APS observational study. 22147897 2012
CUI: C0085278
Disease: Antiphospholipid Syndrome
Antiphospholipid Syndrome 		0.050 GeneticVariation disease BEFREE Sixty patients with SLE were evaluated.Twenty-three patients had antiphospholipid syndrome (APS/SLE). 20516018 2010