NPRL2, NPR2 like, GATOR1 complex subunit, 10641

N. diseases: 45; N. variants: 6
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 Biomarker disease BEFREE This study aims to explore the role of NPRL2 in CRC. 31695423 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 AlteredExpression disease BEFREE CONCLUSIONS NPRL2 overexpression enhances sensitivity to CPT-11 treatment in colon cancer cells, and it may serve as a molecular therapeutic agent to treat patients with CRC. 29519997 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 AlteredExpression disease BEFREE The present study investigated the biological characteristics of the HCT116 and HT29 CRC cell lines overexpressing exogenous NPRL2. 26044952 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 AlteredExpression disease BEFREE NPRL2 protein expression in CRCs was significantly lower than in the adenomas or normal colorectal tissue. 24521741 2014