CES1, carboxylesterase 1, 1066

N. diseases: 80; N. variants: 6
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 Biomarker disease BEFREE So far, the role of mouse Ces1/Ces1g deficiency in atherosclerosis is not elucidated. 29259301 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 AlteredExpression disease BEFREE Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr-/- mice. 24563511 2014
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 Biomarker disease BEFREE Liver-specific cholesteryl ester hydrolase deficiency attenuates sterol elimination in the feces and increases atherosclerosis in ldlr-/- mice. 23744992 2013
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.040 Biomarker disease BEFREE ACAT catalyzes the formation of cholesteryl esters (CE) in monocytes/macrophages, and it promotes the foam cell formation at the early stage of atherosclerosis. 19189937 2009