Schizophrenia
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Dysregulation of pyramidal cell network function by the soma- and axon-targeting inhibitory neurons that contain the calcium-binding protein parvalbumin (PV) represents a core pathophysiological feature of schizophrenia.
|
24628518 |
2015 |
Schizophrenia
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Calcium-binding protein S100B has been implicated in the pathology of bipolar affective disorder (BPAD) and schizophrenia (SZ).
|
21714070 |
2011 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Dione-thiophene conjugate inhibits proliferation and metastasis of nasopharyngeal carcinoma cells through calcium binding protein-P down-regulation.
|
30822709 |
2019 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
In metastatic breast cancers, NFAT5 promotes epithelial-mesenchymal transition (EMT) and invasion of cells by switching on the expression of the calcium binding protein S100A4, and facilitates the angiogenesis of breast epithelial cells and thus the development of metastases by transcriptionally activating vascular endothelial growth factor C (VEGF-C).
|
25311085 |
2014 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The calcium-binding protein S100A4 promotes metastasis in several experimental animal models, including osteosarcoma (OS), and S100A4 protein expression is associated with patient outcome in a number of tumor types.
|
24706307 |
2014 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The calcium-binding protein S100A4 promotes tumor progression and metastasis.
|
21837681 |
2012 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
S100A4, a calcium-binding protein, is implicated in promoting metastasis formation in colon cancer.
|
21685359 |
2011 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The calcium-binding protein S100A4 is a central mediator of metastasis formation in colon cancer.
|
21795396 |
2011 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
High levels of the S100 calcium binding protein S100A4 also called fibroblast specific protein 1 (FSP1) have been established as an inducer of metastasis and indicator of poor prognosis in breast cancer.
|
21195708 |
2011 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Self-association of calcium-binding protein S100A4 and metastasis.
|
19917604 |
2010 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis.
|
18784356 |
2008 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The metastasis associated protein S100A4 is a small calcium binding protein that is associated with metastatic tumors and appears to be a molecular marker for clinical prognosis.
|
15900299 |
2005 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Consideration of clinical studies in conjunction with evidence from experimental animal models reveals that the tyrosine kinase receptor erbB1/EGFR, the calcium binding protein S100A4 and the the cell cycle arrest/apoptosis-inducing p53 protein are amongst the most promising targets for therapy against metastatic disease in patients with bladder cancer.
|
12792907 |
2003 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
S100A4 (MTS1) calcium binding protein in cancer growth, invasion and metastasis.
|
9703888 |
1998 |
Malignant neoplasm of breast
|
0.060 |
Biomarker
|
disease |
BEFREE |
EF Hand Protein IBA2 Promotes Cell Proliferation in Breast Cancers via Transcriptional Control of Cyclin D1.
|
27262171 |
2016 |
Malignant neoplasm of breast
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
S100A7, a member of S100 calcium binding protein family, is highly associated with breast cancer.
|
23000163 |
2012 |
Breast Carcinoma
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
S100A7, a member of S100 calcium binding protein family, is highly associated with breast cancer.
|
23000163 |
2012 |
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
High levels of the S100 calcium binding protein S100A4 also called fibroblast specific protein 1 (FSP1) have been established as an inducer of metastasis and indicator of poor prognosis in breast cancer.
|
21195708 |
2011 |
Breast Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
High levels of the S100 calcium binding protein S100A4 also called fibroblast specific protein 1 (FSP1) have been established as an inducer of metastasis and indicator of poor prognosis in breast cancer.
|
21195708 |
2011 |
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
The presence of the EF-hand-calcium-binding protein S100A4 in the carcinoma cells of the primary tumour is associated with a shorter survival time of a group of breast cancer patients.
|
11875708 |
2002 |
Breast Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
The presence of the EF-hand-calcium-binding protein S100A4 in the carcinoma cells of the primary tumour is associated with a shorter survival time of a group of breast cancer patients.
|
11875708 |
2002 |
Breast Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Northern blot analysis revealed that the level of mRNA for caltractin was higher in breast carcinoma than in corresponding normal tissue in all cases tested (5/5).
|
9824621 |
1998 |
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
The calcium-binding protein S100A2 is expressed in normal breast tissue but downregulated during breast cancer progression.
|
9481475 |
1997 |
Breast Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
The calcium-binding protein S100A2 is expressed in normal breast tissue but downregulated during breast cancer progression.
|
9481475 |
1997 |
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Using antisera raised against partially purified rabbit mammary gland prolactin receptor, we have isolated a cDNA from a T-47D human breast cancer cell expression library which encodes the putative calcium-binding protein, calcyclin.
|
2448309 |
1988 |