Hypercholesterolemia, Familial
|
0.390 |
Biomarker
|
disease |
BEFREE |
We evaluated key steps of the reverse cholesterol transport, ie, cellular free cholesterol efflux, cholesteryl ester transfer protein-mediated cholesteryl ester (CE) transfer from HDL to apolipoprotein B-containing lipoproteins, and hepatic HDL-CE uptake, in patients displaying FH (n = 12) and in healthy normolipidemic control subjects (n = 12).
|
21527752 |
2011 |
Hypercholesterolemia, Familial
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Sex-associated effect of CETP and LPL polymorphisms on postprandial lipids in familial hypercholesterolaemia.
|
19558660 |
2009 |
Hypercholesterolemia, Familial
|
0.390 |
AlteredExpression
|
disease |
LHGDN |
Association between the TaqIB polymorphism in the cholesteryl ester transfer protein gene locus and postprandial plasma lipoprotein levels in heterozygotes for familial hypercholesterolemia.
|
17848121 |
2007 |
Hypercholesterolemia, Familial
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
In the present study, we have investigated the effects of the CETP promoter -1337 C>T and LIPC promoter -514 C>T polymorphisms on serum lipid profiles and risk of coronary atherosclerosis in 206 patients (154 males) with heterozygous FH (familial hypercholesterolaemia).
|
16822236 |
2006 |
Hypercholesterolemia, Familial
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia.
|
16002074 |
2006 |
Hypercholesterolemia, Familial
|
0.390 |
GeneticVariation
|
disease |
LHGDN |
TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.
|
15856070 |
2005 |
Hypercholesterolemia, Familial
|
0.390 |
Biomarker
|
disease |
CTD_human |
Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia.
|
16030523 |
2005 |
Hypercholesterolemia, Familial
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia.
|
15856070 |
2005 |
Hypercholesterolemia, Familial
|
0.390 |
Biomarker
|
disease |
BEFREE |
These results suggest that increased plasma CETP mass concentrations could lead to significant LDL particle remodeling in FH heterozygotes and could contribute to the pathogenesis of atherosclerosis.
|
15026427 |
2004 |
Hypercholesterolemia, Familial
|
0.390 |
Biomarker
|
disease |
BEFREE |
Subjects with familial hypercholesterolemia (FH) have been reported to have higher CETP activities, which could contribute to the lower high-density lipoprotein-cholesterol (HDL-C) levels and increased cardiovascular risk observed in some of these patients.
|
11398140 |
2001 |
Hypercholesterolemia, Familial
|
0.390 |
Biomarker
|
disease |
BEFREE |
Thus, the effect of increased HDL-C levels caused by partial deficiency of CETP is insufficient to prevent CHD in FH.
|
9242969 |
1997 |