OGA, O-GlcNAcase, 10724

N. diseases: 140; N. variants: 6
Disease: anaphylaxis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002792
Disease: anaphylaxis
anaphylaxis 		0.020 Biomarker phenotype BEFREE β-Hexosaminidase is one of the enzymes that is secreted from mast cells via antigen-induced degranulation and has frequently been used as an indicator of anaphylactic reactions. 30297235 2018
CUI: C0002792
Disease: anaphylaxis
anaphylaxis 		0.020 Biomarker phenotype BEFREE The release of mediators of anaphylaxis results showed cinobufagin and osthole can cause anaphylactoid reactions by triggering the release of β-hexosaminidase and histamine via IgE-R. Praeruptorin A and schizandrin A could promote the release of β-hexosaminidase and histamine via MrgprX2 receptor. 29359345 2018